Women are more sensitive to cocaine craving elicited by stimuli associated with relapse.
Ovarian hormones modulate cocaine craving and may therefore function as risk factors or …

The prefrontal cortex, particularly its medial subregions (mPFC), mediates critical functions
such as executive control, behavioral inhibition, and memory formation, with relevance for …

Sex differences in motivation for food rewards, gambling, and drugs of abuse are modulated
by multiple factors, including sensory stimuli, gonadal hormones, and cognitive bias. Cues …

It is not clear if inhibiting the pro-death gene RNA binding motif 5 (RBM5) is neuroprotective
in isolated primary neurons or if it regulates cell survival in a sex-dependent manner. Here …

Sex steroid hormones like estradiol (E2) and progesterone (P4) guide the sexual
organization and activation of the developing brain and control female reproductive …

Estrogen regulates a wide range of neuronal functions in the brain, such as dendritic spine
formation, remodeling of synaptic plasticity, cognition, neurotransmission, and …

Substance abuse is a chronic pathological disorder that negatively affects many health and
neurological processes. A growing body of literature has revealed gender differences in …

Estrogens are believed to modulate cognitive functions in part through the modulation of
synaptic transmission in the cortex and hippocampus. Administration of 17β‐estradiol (E2) …

This systematic review (SR) was aimed at answering two questions:(1) how sex and ovarian
hormones alter behavior associated with cocaine use;(2) which possible neurobiological …

Repeated exposure to addictive drugs leads to the increase in drug-seeking behavior (the
effort to obtain a drug when it is unavailable) and behavioral sensitization (a neuroadaptive …