R Ramautar, GW Somsen, GJ de Jong - Electrophoresis, 2009 - Wiley Online Library
An overview of the use of CE‐MS in the field of metabolomics is provided. Metabolomics is concerned with the comprehensive analysis of endogenous low‐molecular‐weight …
K Nakahigashi, Y Toya, N Ishii, T Soga… - Molecular systems …, 2009 - embopress.org
Central carbon metabolism is a basic and exhaustively analyzed pathway. However, the intrinsic robustness of the pathway might still conceal uncharacterized reactions. To test this …
Fermentative hydrogen production (FHP) has received a great R & D interest in recent decades, as it offers a potential means of producing H2 from a variety of renewable …
N Zamboni - Current opinion in biotechnology, 2011 - Elsevier
Experimental determination of in vivo metabolic rates by methods of 13C metabolic flux analysis is a pivotal approach to unravel structure and regulation of metabolic networks, in …
Metabolic flux analysis via 13C labeling (13C MFA) quantitatively tracks metabolic pathway activity and determines overall enzymatic function in cells. Three core techniques are …
M Rühl, B Rupp, K Nöh, W Wiechert… - Biotechnology and …, 2012 - Wiley Online Library
Experimental determination of fluxes by 13C‐tracers relies on detection of 13C‐patterns in metabolites or by‐products. In the field of 13C metabolic flux analysis, the most recent …
V Kostal, J Katzenmeyer, EA Arriaga - Analytical chemistry, 2008 - ACS Publications
For the period January 2006 to December 2007, Web of Science reports∼ 4800 hits on capillary electrophoresis (CE) including 410 reviews. Because of the prominence of CE …
Since most bio‐production processes are conducted in a batch or fed‐batch manner, the evaluation of metabolism with respect to time is highly desirable. Toward this aim, we …
C Barbas, EP Moraes, A Villasenor - Journal of pharmaceutical and …, 2011 - Elsevier
Metabolomics, understood as a data driven strategy trying to find markers of a situation under study without a priori hypothesis, has rapidly caught the attention and evolved from …