The WRKY proteins are a superfamily of transcription factors with up to 100 representatives
in Arabidopsis. Family members appear to be involved in the regulation of various physio …

In order to extract the maximum amount of information from the rapidly accumulating
genome sequences, all conserved genes need to be classified according to their …

Long-read, single-molecule real-time (SMRT) sequencing is routinely used to finish
microbial genomes, but available assembly methods have not scaled well to larger …

The flowering plant Arabidopsis thaliana is an important model system for identifying genes
and determining their functions. Here we report the analysis of the genomic sequence of …

Accurate multiple alignments of 86 domains that occur in signaling proteins have been
constructed and used to provide a Web-based tool (SMART: simple modular architecture …

DNA sequencing is one of the most important technologies in bioscience today. Whole-
genome approaches (1) and human expressed sequence tag (EST) sequencing (2) have …

The system SOSUI for the discrimination of membrane proteins and soluble ones together
with the prediction of transmembrane helices was developed, in which the accuracy of the …

We report on the quality of a whole-genome assembly of Drosophila melanogaster and the
nature of the computer algorithms that accomplished it. Three independent external data …

Since the completion of the genome sequence of Saccharomyces cerevisiae in 1996 (refs),
there has been a large increase in complete genome sequences, accompanied by great …

Technologies to measure whole-genome mRNA abundances 1, 2, 3 and methods to
organize and display such data 4, 5, 6, 7, 8, 9, 10 are emerging as valuable tools for systems …