Targeting tumor necrosis factor alpha for Alzheimer's disease

B Decourt, DK Lahiri… - Current Alzheimer …, 2017 - ingentaconnect.com
Alzheimer's disease (AD) affects an estimated 44 million individuals worldwide, yet no
therapeutic intervention is available to stop the progression of the dementia …

managing the adverse events caused by anti‐TNF therapy in inflammatory bowel disease

UN Shivaji, CL Sharratt, T Thomas… - Alimentary …, 2019 - Wiley Online Library
Background Biological therapy is currently widely used to treat IBD. Infliximab, adalimumab
and golimumab are currently licensed anti‐TNF therapies. Biosimilar anti‐TNF monoclonal …

The safety of vedolizumab for ulcerative colitis and Crohn's disease

JF Colombel, BE Sands, P Rutgeerts, W Sandborn… - Gut, 2017 - gut.bmj.com
Objective Vedolizumab is a gut-selective antibody to α4β7 integrin for the treatment of
ulcerative colitis (UC) and Crohn's disease (CD). We report an integrated summary of the …

Anti–tumor necrosis factor therapy and incidence of Parkinson disease among patients with inflammatory bowel disease

I Peter, M Dubinsky, S Bressman, A Park, C Lu… - JAMA …, 2018 - jamanetwork.com
Importance Despite established genetic and pathophysiologic links between inflammatory
bowel disease (IBD) and Parkinson disease (PD), clinical data supporting this association …

Harnessing tumor necrosis factor alpha to achieve effective cancer immunotherapy

MF Mercogliano, S Bruni, F Mauro, PV Elizalde… - Cancers, 2021 - mdpi.com
Simple Summary Inflammation has been acknowledged as one of the causes of increased
cancer risk. Among the pro-inflammatory mediators, tumor necrosis factor alpha (TNFα) has …

Therapeutic strategies for treatment of inflammation-related depression

M Adzic, Z Brkic, M Mitic, E Francija… - Current …, 2018 - ingentaconnect.com
Background: Mounting evidence demonstrates enhanced systemic levels of inflammatory
mediators in depression, indicating that inflammation may play a role in the etiology and …

Autoimmune diseases induced by biological agents. A review of 12,731 cases (BIOGEAS Registry)

M Pérez-De-Lis, S Retamozo… - Expert opinion on …, 2017 - Taylor & Francis
Introduction: Biological drugs are therapies designed to target a specific molecule of the
immune system that have been linked with the development of autoimmune diseases. Areas …

Effectiveness and tolerance of anti‐inflammatory drugs' add‐on therapy in major mental disorders: a systematic qualitative review

G Fond, N Hamdani, F Kapczinski… - Acta Psychiatrica …, 2014 - Wiley Online Library
Objective To provide a systematic review of the literature regarding the efficacy of anti‐
inflammatory drugs in three major mental disorders [major depressive disorder (MDD) …

Focus on anti-tumour necrosis factor (TNF)-α-related autoimmune diseases

LR Lopetuso, C Cuomo, I Mignini, A Gasbarrini… - International Journal of …, 2023 - mdpi.com
Anti-tumour necrosis factor (TNF)-α agents have been increasingly used to treat patients
affected by inflammatory bowel disease and dermatological and rheumatologic inflammatory …

Neurology of inflammatory bowel disease

JM Ferro, MO Santos - Journal of the Neurological Sciences, 2021 - Elsevier
Inflammatory bowel diseases (IBD) are chronic inflammatory conditions affecting the
digestive system, comprising two main distinctive entities, ulcerative colitis (UC) and Crohn's …