Pseudomonas aeruginosa is a metabolically versatile bacterium that is found in a wide
range of biotic and abiotic habitats. It is a major human opportunistic pathogen causing …

The phosphoenolpyruvate (PEP): carbohydrate phosphotransferase system (PTS) is found
only in bacteria, where it catalyzes the transport and phosphorylation of numerous …

Leptospirosis, caused by spirochetes of the genus Leptospira, is a globally widespread,
neglected and emerging zoonotic disease. While whole genome analysis of individual …

Streptomyces coelicolor is a representative of the group of soil-dwelling, filamentous
bacteria responsible for producing most natural antibiotics used in human and veterinary …

Some bacteria have the remarkable capacity to fix atmospheric nitrogen to ammonia under
ambient conditions, a reaction only mimicked on an industrial scale by a chemical process …

Bacteria use their genetic material with great effectiveness to make the right products in the
correct amounts at the appropriate time. Studying bacterial transcription initiation in …

▪ Abstract Promoter recognition in eubacteria is carried out by the initiation factor sigma,
which binds RNA polymerase and initiates transcription. Cells have one housekeeping …

Gene expression occurs in two essential steps: transcription and translation. In bacteria, the
two processes are tightly coupled in time and space, and highly regulated. Tight regulation …

▪ Abstract Nitrogen limitation in Escherichia coli controls the expression of about 100 genes
of the nitrogen regulated (Ntr) response, including the ammonia-assimilating glutamine …

We present a comprehensive overview of the hierarchical network of intracellular processes
revolving around central nitrogen metabolism in Escherichia coli. The hierarchy intertwines …