Thiazole, a five-membered heteroaromatic ring, is an important scaffold of a large number of
synthetic compounds. Its diverse pharmacological activity is reflected in many clinically …

Indole derivatives are among the most useful and interesting heterocycles employed in drug
discovery and medicinal chemistry. In addition, flow chemistry and flow technology are …

The resistance of microorganisms to antimicrobials has endangered the health of many
people across the world. Overcoming the resistance problem will require the invention of …

Non-steroidal anti-inflammatory drugs (NSAIDs) are commonly used therapeutic agents that
exhibit frequent and sometimes severe adverse effects, including gastrointestinal ulcerations …

As ribonucleotide reductase (RNR) plays a crucial role in nucleic acid metabolism, it is an
important target for anticancer therapy. The thiosemicarbazone Triapine is an efficient R2 …

Amino acid polyoxometalate nanoparticles-embedded microcapsules were in situ fabricated
by layer-by-layer (LbL) self-assembly method [isopolyoxometalate, Mo8O26· nH2O; amino …

Efficient and inexpensive synthesis of 2‐amino‐5‐arylazothiazoles derivatives was made in
simple steps and in good yields. Spectral and physical analyses techniques were applied to …

Increased levels of free fatty acid (FFA)-induced endothelial dysfunction play an important
role in the initiation and development of atherosclerosis. Feprazone is a nonsteroidal anti …

One new indolocarbazole, 3-hydroxy-K252d (3), together with the recently reported 3-
hydroxyholyrine A (1) and 3′-N-acetyl-3-hydroxyholyrine A (2), were obtained by feeding a …

A facile, green, one-pot multicomponent synthesis strategy was employed to fabricate novel
thiazole scaffolds incorporating phthalazine, pyridazine, and pyrido-pyridazine derivatives …