[HTML][HTML] Biomarkers as biomedical bioindicators: approaches and techniques for the detection, analysis, and validation of novel Biomarkers of diseases

A Ahmad, M Imran, H Ahsan - Pharmaceutics, 2023 - mdpi.com
A biomarker is any measurable biological moiety that can be assessed and measured as a
potential index of either normal or abnormal pathophysiology or pharmacological responses …

MALDI-TOF mass spectrometry in clinical analysis and research

D Li, J Yi, G Han, L Qiao - ACS Measurement Science Au, 2022 - ACS Publications
In the decade after being awarded the Nobel Prize in Chemistry in 2002, matrix-assisted
laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS) has been …

Applications of machine learning in cancer prediction and prognosis

JA Cruz, DS Wishart - Cancer informatics, 2006 - journals.sagepub.com
Machine learning is a branch of artificial intelligence that employs a variety of statistical,
probabilistic and optimization techniques that allows computers to “learn” from past …

Mechanism-based profiling of enzyme families

MJ Evans, BF Cravatt - Chemical reviews, 2006 - ACS Publications
Genome sequencing projects have ushered biological research into a new age where
scientists are confronted with the daunting undertaking of assigning functions to the full …

Exocrine pancreatic cancer: symptoms at presentation and their relation to tumour site and stage

M Porta, X Fabregat, N Malats, L Guarner… - Clinical and …, 2005 - Springer
Introduction. The need to detect pancreatic cancer at earlier stages is undisputed. We
recorded the signs and symptoms of patients presenting with exocrine pancreatic cancer …

Nano-oncology: drug delivery, imaging, and sensing

NG Portney, M Ozkan - Analytical and bioanalytical chemistry, 2006 - Springer
Innovation in the last decade has endowed nanotechnology with an assortment of tools for
delivery, imaging, and sensing in cancer research—stealthy nanoparticle vectors circulating …

[HTML][HTML] Ionizing radiation biomarkers for potential use in epidemiological studies

E Pernot, J Hall, S Baatout, MA Benotmane… - … Research/Reviews in …, 2012 - Elsevier
Ionizing radiation is a known human carcinogen that can induce a variety of biological
effects depending on the physical nature, duration, doses and dose-rates of exposure …

[HTML][HTML] Learning classification models of cognitive conditions from subtle behaviors in the digital clock drawing test

W Souillard-Mandar, R Davis, C Rudin, R Au, DJ Libon… - Machine learning, 2016 - Springer
Abstract The Clock Drawing Test—a simple pencil and paper test—has been used for more
than 50 years as a screening tool to differentiate normal individuals from those with cognitive …

[HTML][HTML] Identification of diagnostic markers for tuberculosis by proteomic fingerprinting of serum

D Agranoff, D Fernandez-Reyes, MC Papadopoulos… - The Lancet, 2006 - thelancet.com
Background We investigated the potential of proteomic fingerprinting with mass
spectrometric serum profiling, coupled with pattern recognition methods, to identify …

[HTML][HTML] Statistical and computational methods for comparative proteomic profiling using liquid chromatography-tandem mass spectrometry

J Listgarten, A Emili - Molecular & Cellular Proteomics, 2005 - ASBMB
The combined method of LC-MS/MS is increasingly being used to explore differences in the
proteomic composition of complex biological systems. The reliability and utility of such …