Giardia is a flagellated protozoan parasite that has to face different microenvironments
during its life cycle in order to survive. All cells exchange materials with the extracellular …

Members of Myxozoa, a parasitic metazoan taxon, have considerable detrimental effects on
fish hosts and also have been associated with human food-borne illness. Little is known …

The manner in which membrane-associated proteins interact with the membrane defines
their subcellular fate and function. This interaction relies on the characteristics of the …

Giardiasis is a neglected parasitic disease that affects primarily children, in whom it delays
physical and mental development. The pathophysiology of giardiasis in not well understood …

Background Giardia lamblia, a parasitic protist of the Metamonada supergroup, has evolved
one of the most diverged endocytic compartment systems investigated so far. Peripheral …

Lactoferrin (LF) is an 80 KDa iron-binding glycoprotein that plays a significant role in the
innate immune system and is considered to be an important microbicide molecule. It has …

Giardia lamblia is a flagellated protozoan enteroparasite transmitted as an environmentally
resistant cyst. Trophozoites attach to the small intestine of vertebrate hosts and proliferate by …

In the protozoa parasite Giardia lamblia, endocytosis and lysosomal protein trafficking are
vital parasite-specific processes that involve the action of the adaptor complexes AP-1 and …

In Giardia, lysosome-like peripheral vacuoles (PVs) need to specifically coordinate their
endosomal and lysosomal functions to be able to successfully perform endocytosis, protein …

The early branching Giardia lamblia has highly polarized vacuoles, located underneath the
plasma membrane, which have at least some of the characteristics of endosomes and of …