Eukaryotic chromosome DNA replication: where, when, and how?

H Masai, S Matsumoto, Z You… - Annual review of …, 2010 - annualreviews.org
DNA replication is central to cell proliferation. Studies in the past six decades since the
proposal of a semiconservative mode of DNA replication have confirmed the high degree of …

An epigenetic framework for neurodevelopmental disorders: from pathogenesis to potential therapy

MJ Millan - Neuropharmacology, 2013 - Elsevier
Neurodevelopmental disorders (NDDs) are characterized by aberrant and delayed early-life
development of the brain, leading to deficits in language, cognition, motor behaviour and …

Tourette's syndrome: from behaviour to biology

HS Singer - The Lancet Neurology, 2005 - thelancet.com
Tourette's syndrome (TS) is a chronic neuropsychiatric disorder characterised by motor and
vocal tics. Diagnosis is based solely on clinical criteria. The prevalence of this syndrome is …

Tourette syndrome and tic disorders: a decade of progress

JE Swain, L Scahill, PJ Lombroso, RA King… - Journal of the American …, 2007 - Elsevier
OBJECTIVE:: This is a review of progress made in the understanding of Tourette syndrome
(TS) during the past decade including models of pathogenesis, state-of-the-art assessment …

Disruption of contactin 4 (CNTN4) results in developmental delay and other features of 3p deletion syndrome

T Fernandez, T Morgan, N Davis, A Klin… - The American Journal of …, 2004 - cell.com
3p deletion syndrome is a rare contiguous-gene disorder involving the loss of the telomeric
portion of the short arm of chromosome 3 and characterized by developmental delay, growth …

The genetics of Tourette syndrome: a review

JA O'Rourke, JM Scharf, D Yu, DL Pauls - Journal of psychosomatic …, 2009 - Elsevier
OBJECTIVES: This article summarizes and evaluates recent advances in the genetics of
Gilles de la Tourette syndrome (GTS). METHODS: This is a review of recent literature …

Tic disorders

JF Leckman, MH Bloch - Rutter's Child and Adolescent …, 2015 - Wiley Online Library
Tourette syndrome (TS) and related conditions encompass a heterogeneous and
multidimensional spectrum of clinical presentations. Early on there was the hope, indeed the …

DNA replication timing, genome stability and cancer: late and/or delayed DNA replication timing is associated with increased genomic instability

N Donley, MJ Thayer - Seminars in cancer biology, 2013 - Elsevier
Normal cellular division requires that the genome be faithfully replicated to ensure that
unaltered genomic information is passed from one generation to the next. DNA replication …

Pathogenetic model for Tourette syndrome delineates overlap with related neurodevelopmental disorders including Autism

RA Clarke, S Lee, V Eapen - Translational psychiatry, 2012 - nature.com
Tourette syndrome (TS) is a highly heritable neuropsychiatric disorder characterised by
motor and vocal tics. Despite decades of research, the aetiology of TS has remained elusive …

The genetic basis of Gilles de la Tourette Syndrome

P Paschou - Neuroscience & Biobehavioral Reviews, 2013 - Elsevier
Gilles de la Tourette Syndrome (TS) is a neuropsychiatric disorder that is caused by a likely
complex genetic basis, interacting with environmental factors. Just as multiple large scale …