In mammals, transcriptional inactivation of one X chromosome in female compensates for the dosage of X-linked gene expression between the sexes. Additionally, it is believed that …
The early mammalian germ cell lineage is characterized by extensive epigenetic reprogramming, which is required for the maturation into functional eggs and sperm. In …
Recent studies have provided substantial evidence supporting Ohno's hypothesis that upregulation of active X chromosome genes balances the dosage of X-linked gene …