[HTML][HTML] From a single steroid to the steroidome: Trends and analytical challenges

E Olesti, J Boccard, G Visconti, V Gonzalez-Ruiz… - The Journal of steroid …, 2021 - Elsevier
For several decades now, the analysis of steroids has been a key tool in the diagnosis and
monitoring of numerous endocrine pathologies. Thus, the available methods used to …

Approaches in metabolomics for regulatory toxicology applications

E Olesti, V González-Ruiz, MF Wilks, J Boccard… - Analyst, 2021 - pubs.rsc.org
Innovative methodological approaches are needed to conduct human health and
environmental risk assessments on a growing number of marketed chemicals. Metabolomics …

Collision cross section (CCS) database: an additional measure to characterize steroids

M Hernández-Mesa, B Le Bizec, F Monteau… - Analytical …, 2018 - ACS Publications
Ion mobility spectrometry enhances the performance characteristics of liquid
chromatography–mass spectrometry workflows intended to steroid profiling by providing a …

The use of gas chromatography–high resolution mass spectrometry for suspect screening and non-targeted analysis of per-and polyfluoroalkyl substances

JS Casey, SR Jackson, J Ryan, SR Newton - Journal of Chromatography A, 2023 - Elsevier
This study is a workflow development for the analysis, identification, and categorization of
per-and polyfluoroalkyl substances (PFAS) using gas chromatography-high resolution mass …

Mass spectrometric fragmentation of trimethylsilyl and related alkylsilyl derivatives

DJ Harvey, P Vouros - Mass spectrometry reviews, 2020 - Wiley Online Library
This review describes the mass spectral fragmentation of trimethylsilyl (TMS) and related
alkylsilyl derivatives used for preparing samples for analysis, mainly by combined gas …

GC/MS in recent years has defined the normal and clinically disordered steroidome: will it soon be surpassed by LC/tandem MS in this role?

C Shackleton, OJ Pozo, J Marcos - Journal of the Endocrine …, 2018 - academic.oup.com
Gas chromatography/mass spectrometry (GC/MS) has been used for steroid analysis since
the 1960s. The advent of protective derivatization, capillary columns, and inexpensive …

Multidimensional separations of intact phase II steroid metabolites utilizing LC–ion mobility–HRMS

DE Davis Jr, KL Leaptrot, DC Koomen, JC May… - Analytical …, 2021 - ACS Publications
The detection and unambiguous identification of anabolic-androgenic steroid metabolites
are essential in clinical, forensic, and antidoping analyses. Recently, sulfate phase II steroid …

Mass spectrometric detection of 27-hydroxycholesterol in breast cancer exosomes

H Roberg-Larsen, K Lund, KE Seterdal… - The Journal of steroid …, 2017 - Elsevier
Exosomes from cancer cells are rich sources of biomarkers and may contain elevated levels
of lipids of diagnostic value. 27-Hydroxycholesterol (27-OHC) is associated with proliferation …

Determination of the steroid profile in alternative matrices by liquid chromatography tandem mass spectrometry

A Gomez-Gomez, J Miranda, G Feixas… - The Journal of Steroid …, 2020 - Elsevier
The simultaneous determination of a broad panel of steroids provides more accurate
information about the hormonal status than the detection of a single hormone. For that …

Dried blood spots in doping analysis

Y Yuan, Y Xu, J Lu - Bioanalysis, 2021 - Taylor & Francis
A series of dried blood spot (DBS) detection methods for doping agents have been
developed in the last two decades. The DBS technique minimizes invasiveness and reduces …