Drug repurposing in non-small cell lung carcinoma: old solutions for new problems
Lung cancer is the second most common cancer and the leading cause of cancer-related
deaths in 2022. The majority (80%) of lung cancer cases belong to the non-small cell lung …
deaths in 2022. The majority (80%) of lung cancer cases belong to the non-small cell lung …
Material and design toolkit for drug delivery: state of the art, trends, and challenges
The nanomaterial and related toolkit have promising applications for improving human
health and well-being. Nanobased drug delivery systems use nanoscale materials as …
health and well-being. Nanobased drug delivery systems use nanoscale materials as …
Combination of indomethacin with nanostructured lipid carriers for effective anticancer therapy
V Thiruchenthooran, M Espina… - International journal …, 2024 - Taylor & Francis
Purpose The anticancer potential of indomethacin and other nonsteroidal anti-inflammatory
drugs (NSAIDs) in vitro, in vivo, and in clinical trials is well known and widely reported in the …
drugs (NSAIDs) in vitro, in vivo, and in clinical trials is well known and widely reported in the …
Nano-mediated strategy for targeting and treatment of non-small cell lung cancer (NSCLC)
S Ashique, A Garg, N Mishra, N Raina, LC Ming… - Naunyn-Schmiedeberg's …, 2023 - Springer
Lung cancer is the most common type of cancer, with over 2.1 million cases diagnosed
annually worldwide. It has a high incidence and mortality rate, leading to extensive research …
annually worldwide. It has a high incidence and mortality rate, leading to extensive research …
Folate receptor-targeted indomethacin-loaded gold nanoparticles enhance drug chemotherapeutic efficacy in glioblastoma cells and spheroids
Glioblastoma is a highly malignant brain cancer with a poor survival rate. Increasing
evidence demonstrates the anticancer activity, including anti-glioma activity, of indomethacin …
evidence demonstrates the anticancer activity, including anti-glioma activity, of indomethacin …
Lipid-Based inhalable micro-and nanocarriers of active agents for treating non-small-cell lung cancer
Non-small-cell lung cancer (NSCLC) afflicts about 2 million people worldwide, with both
genetic (familial) and environmental factors contributing to its development and spread. The …
genetic (familial) and environmental factors contributing to its development and spread. The …
Lipid polymer hybrid nanoparticles against lung cancer and their application as inhalable formulation
Lung cancer is a leading cause of global cancer mortality, often treated with
chemotherapeutic agents. However, conventional approaches such as oral or intravenous …
chemotherapeutic agents. However, conventional approaches such as oral or intravenous …
A novel therapeutic outlook: Classification, applications and challenges of inhalable micron/nanoparticle drug delivery systems in lung cancer
L Xie, D Xie, Z Du, S Xue, K Wang… - International …, 2024 - spandidos-publications.com
Lung cancer represents a marked global public health concern. Despite existing treatment
modalities, the average 5‑year survival rate for patients with patients with lung cancer is …
modalities, the average 5‑year survival rate for patients with patients with lung cancer is …
Emerging COX-2 inhibitors-based nanotherapeutics for cancer diagnosis and treatment
R Huang, Y Jiang, B Zhang, X Li, H Liu, Y Wang - Biomaterials, 2024 - Elsevier
Increasing evidence has showed that tumorigenesis is closely linked to inflammation,
regulated by multiple signaling pathways. Among these, the cyclooxygenase …
regulated by multiple signaling pathways. Among these, the cyclooxygenase …
Chitosan/bovine serum albumin layer-by-layer assembled particles for non-invasive inhaled drug delivery to the lungs
Abstract Layer-by-Layer (LbL) assembly of polyelectrolytes on a solid core particle is a well-
established technique used to deliver drugs, proteins, regenerative medicines …
established technique used to deliver drugs, proteins, regenerative medicines …