Every day, analytical and bio-analytical chemists make sustained efforts to improve the
sensitivity, specificity, robustness, and reproducibility of their methods. Especially in targeted …

The focus of this article is to review the recent advances in proteome analysis of human
body fluids, including plasma/serum, urine, cerebrospinal fluid, saliva, bronchoalveolar …

Background: Matrix-assisted laser desorption/ionization time-of-flight mass spectrometry
(MALDI-TOF MS) and the related technique, surface-enhanced laser desorption/ionization …

The low-molecular-weight range of the circulatory proteome is termed the'peptidome', and
could be a rich source of cancer-specific diagnostic information because it is a'recording'of …

Mass spectrometry platforms have attracted a lot of interest in the last 2 decades as profiling
tools for native peptides and proteins with clinical potential. However, limitations associated …

In this article, we present an overview of the different strategies for sample preparation for
identification by mass spectrometry (MS) of biomarkers from serum and/or plasma. We …

Background: Protein profiling with high-throughput sample preparation and MALDI-TOF MS
analysis is a new potential tool for diagnosis of human diseases. However, analytical …

Objective: Early detection is the only promising approach to significantly improve the survival
of patients with pancreatic cancer (PCa). Noninvasive tools for the diagnosis, prognosis, and …

Alzheimer's disease (AD) is the most important cause of dementia in the elderly. The
molecular alterations preceding this neurodegenerative pathology may take place even 20 …

Public–Private Partnerships (PPP or 3Ps) allow the public sector to seek alternative funding
and expertise from the private sector during procurement processes. Such partnerships, if …