Depriving iron supply to the virus represents a promising adjuvant therapeutic against viral survival

W Liu, S Zhang, S Nekhai, S Liu - Current clinical microbiology reports, 2020 - Springer
Purpose of the review The ongoing outbreak of novel coronavirus pneumonia (COVID-19)
caused by the 2019 novel coronavirus (SARS-CoV-2) in China is lifting widespread …

The role of ferroptosis in virus infections

J Wang, J Zhu, S Ren, Z Zhang, K Niu, H Li… - Frontiers in …, 2023 - frontiersin.org
Regulated cell death (RCD) is a strategy employed by host cells to defend invasions of
pathogens, such as viruses and bacteria. Ferroptosis is a type of RCD characterized by …

[HTML][HTML] Low transferrin levels predict heightened inflammation in patients with COVID-19: New insights

C Claise, J Saleh, M Rezek, S Vaulont… - International Journal of …, 2022 - Elsevier
Objectives Mounting evidence links hyperinflammation in gravely ill patients to low serum
iron levels and hyperferritinemia. However, little attention has been paid to other iron …

Iron saturation drives lactoferrin effects on oxidative stress and neurotoxicity induced by HIV-1 Tat

G Ianiro, V D'Ezio, L Carpinelli, C Casella… - International Journal of …, 2023 - mdpi.com
The Trans-Activator of Transcription (Tat) of Human Immunodeficiency Virus (HIV-1) is
involved in virus replication and infection and can promote oxidative stress in human …

[HTML][HTML] With me or against me: Tumor suppressor and drug resistance activities of SAMHD1

N Herold, SG Rudd, K Sanjiv, J Kutzner… - Experimental …, 2017 - Elsevier
Highlights•Sterile alpha motif and histidine/aspartic acid domain-containing protein 1 is a
deoxyribonucleoside triphosphate (dNTP) triphosphohydrolase that is involved in cellular …

Egg yolk antibody combined with bismuth-based quadruple therapy in Helicobacter pylori infection rescue treatment: a single-center, randomized, controlled study

S Cheng, H Li, J Luo, J Chi, W Zhao, J Lin… - Frontiers in …, 2023 - frontiersin.org
Background The increasing antibiotic resistance is the main issue causing Helicobacter
pylori (H. pylori) eradication failure. As a nutritional supplement, Egg Yolk Antibody (Ig Y) …

Role of divalent cations in HIV-1 replication and pathogenicity

N Khan, X Chen, JD Geiger - Viruses, 2020 - mdpi.com
Divalent cations are essential for life and are fundamentally important coordinators of
cellular metabolism, cell growth, host-pathogen interactions, and cell death. Specifically, for …

[HTML][HTML] Circulating iron in patients with sickle cell disease mediates the release of neutrophil extracellular traps

K Van Avondt, M Schimmel, I Bulder… - Transfusion Medicine …, 2023 - karger.com
Introduction: Neutrophils promote chronic inflammation and release neutrophil extracellular
traps (NETs) that can drive inflammatory responses. Inflammation influences progression of …

HIV-1 Tat phosphorylation on Ser-16 residue modulates HIV-1 transcription

A Ivanov, X Lin, T Ammosova, AV Ilatovskiy, N Kumari… - Retrovirology, 2018 - Springer
Background HIV-1 transcription activator protein Tat is phosphorylated in vitro by CDK2 and
DNA-PK on Ser-16 residue and by PKR on Tat Ser-46 residue. Here we analyzed Tat …

Protein phosphatase-1-targeted small molecules, iron chelators and curcumin analogs as HIV-1 antivirals

X Lin, T Ammosova, N Kumari… - Current pharmaceutical …, 2017 - ingentaconnect.com
Background: Despite efficient suppression of HIV-1 replication, current antiviral drugs are
not able to eradicate HIV-1 infection. Permanent HIV-1 suppression or complete eradication …