The host response to biomaterials has been studied for decades. Largely, the interaction of
host immune cells, macrophages in particular, with implanted materials has been …

At least 468 individual genes have been manipulated by molecular methods to study their
effects on the initiation, promotion, and progression of atherosclerosis. Most clinicians and …

As one of the cornerstones of innate immunity, the complement system has long been
implicated in the pathogenesis of atherosclerosis. Growing evidence demonstrates the …

Monocyte and macrophage phenotypic diversity is important in atherogenesis. More work is
needed to define consistent marker sets for the different foam cell phenotypes in …

Hypercholesterolemia is one of the major risk factors for the development of cardiovascular
disease. Atherosclerosis resulting from hypercholesterolemia causes many serious …

Despite recent medical advances, atherosclerosis is a global burden accounting for
numerous deaths and hospital admissions. Immune-mediated inflammation is a major …

Atherosclerosis is a chronic inflammatory disease and the complement system plays a
central role in innate immunity. Increasing evidence exists that the complement system is …

Next-generation biomaterials are expected to possess both desirable mechanical features
and unique biological functions. Recently, two plant-derived glucomannans (GMs)—Konjac …

Atherosclerosis is nowadays recognized as a chronic inflammatory disease of large arteries.
In recent years, cellular and molecular biology studies on atherosclerosis confirmed that the …

Proteins are frequently modified by complex carbohydrates (glycans) that play central roles
in maintaining the structural and functional integrity of cells and tissues in humans and lower …