Role of reactive oxygen species in aging and age-related diseases: A review

MI Anik, N Mahmud, AA Masud, MI Khan… - ACS Applied Bio …, 2022 - ACS Publications
Research on the role of reactive oxygen species (ROS) in the aging process has advanced
significantly over the last two decades. In light of recent findings, ROS takes part in the aging …

The role of oxidative stress-mediated inflammation in the development of T2DM-induced diabetic nephropathy: possible preventive action of tannins and other …

G Sahakyan, A Vejux, N Sahakyan - Molecules, 2022 - mdpi.com
Diabetic nephropathy is manifested in more than 10% of people with diabetes. It is a
common cause of kidney failure and end-stage kidney disease. Understanding of …

[HTML][HTML] Involvement of muscle satellite cell dysfunction in neuromuscular disorders: Expanding the portfolio of satellite cell-opathies

M Ganassi, PS Zammit - European Journal of Translational …, 2022 - ncbi.nlm.nih.gov
Neuromuscular disorders are a heterogeneous group of acquired or hereditary conditions
that affect striated muscle function. The resulting decrease in muscle strength and motility …

A cross-talk between sestrins, chronic inflammation and cellular senescence governs the development of age-associated sarcopenia and obesity

G Livshits, A Kalinkovich - Ageing Research Reviews, 2023 - Elsevier
The rapid increase in both the lifespan and proportion of older adults is accompanied by the
unprecedented rise in age-associated chronic diseases, including sarcopenia and obesity …

FSHD muscle shows perturbation in fibroadipogenic progenitor cells, mitochondrial function and alternative splicing independently of inflammation

EN Engquist, A Greco, LAB Joosten… - Human Molecular …, 2024 - academic.oup.com
Facioscapulohumeral muscular dystrophy (FSHD) is a prevalent, incurable myopathy. FSHD
is highly heterogeneous, with patients following a variety of clinical trajectories, complicating …

A NIR pH sensitive fluorescent strategy for ratiometric detection of reactive oxygen species and its application in the imaging of arthritis

H Liu, W Chen, W Yuan, J Gao, Q Zhang… - Sensors and Actuators B …, 2023 - Elsevier
Inflammation, a common disease triggered by oxidative stress, could produce reactive
oxygen species (ROSs) of high level in tissues with a wide pH range. However, non-invasive …

Pleiotropic signaling by reactive oxygen species concerted with dietary phytochemicals and microbial-derived metabolites as potent therapeutic regulators of the …

T Murai, S Matsuda - Antioxidants, 2023 - mdpi.com
The excessive generation of reactive oxygen species (ROS) plays a pivotal role in the
pathogenesis of diseases. ROS are central to cellular redox regulation and act as second …

Revisiting resveratrol as an osteoprotective agent: molecular evidence from in vivo and in vitro studies

H Ahmad Hairi, PA Jayusman, AN Shuid - Biomedicines, 2023 - mdpi.com
Resveratrol (RSV)(3, 5, 4′-trihydroxystilbene) is a stilbene found in abundance in berry
fruits, peanuts, and some medicinal plants. It has a diverse range of pharmacological …

Maqui berry and ginseng extracts reduce cigarette smoke-induced cell injury in a 3D bone co-culture model

H Guo, W Weng, S Zhang, H Rinderknecht, B Braun… - Antioxidants, 2022 - mdpi.com
Cigarette smoking-induced oxidative stress has harmful effects on bone metabolism. Maqui
berry extract (MBE) and ginseng extract (GE) are two naturally occurring antioxidants that …

The transcription factor DUX4 orchestrates translational reprogramming by broadly suppressing translation efficiency and promoting expression of DUX4-induced …

DC Hamm, EM Paatela, SR Bennett, CJ Wong… - PLoS …, 2023 - journals.plos.org
Translational control is critical for cell fate transitions during development, lineage
specification, and tumorigenesis. Here, we show that the transcription factor double …