Environmental bacteria as triggers to brain disease: Possible mechanisms of toxicity and associated human risk
A Courtier, D Potheret, P Giannoni - Life Sciences, 2022 - Elsevier
Aims Brain disease, in its many forms, has recently demonstrated a great socio-economic
impact and represents one of the hardest challenges of present research. Although each …
impact and represents one of the hardest challenges of present research. Although each …
Bee venom (Apis mellifera L.) rescues zinc oxide nanoparticles induced neurobehavioral and neurotoxic impact via controlling neurofilament and GAP-43 in rat brain
NZH Eleiwa, MAA Ali, EN Said, MMM Metwally… - … Science and Pollution …, 2023 - Springer
This study investigated the possible beneficial role of the bee venom (BV, Apis mellifera L.)
against zinc oxide nanoparticles (ZNPs)-induced neurobehavioral and neurotoxic impacts in …
against zinc oxide nanoparticles (ZNPs)-induced neurobehavioral and neurotoxic impacts in …
Uptake of β-N-methylamino-L-alanine (BMAA) into glutamate-specific synaptic vesicles: Exploring the validity of the excitotoxicity mechanism of BMAA
R van Onselen, TG Downing - Neuroscience Letters, 2024 - Elsevier
The first mechanism of toxicity proposed for the cyanobacterial neurotoxin β-N-methylamino-
L-alanine (BMAA) was excitotoxicity, and this was supported by numerous in vitro studies in …
L-alanine (BMAA) was excitotoxicity, and this was supported by numerous in vitro studies in …
β-N-methylamino-l-alanine is a non-competitive inhibitor of vesicular monoamine transporter 2
C Kennedy, R Van Onselen, TG Downing - Toxicon, 2023 - Elsevier
The neurotoxic, non-proteinogenic amino acid β-N-methylamino-l-alanine (BMAA) has been
implicated in the development of neurodegenerative diseases; however, the mechanism (s) …
implicated in the development of neurodegenerative diseases; however, the mechanism (s) …
[HTML][HTML] Protection against β-N-methylamino-l-alanineꟷinduced vesicular monoamine transporter 2 inhibition by hydroxyl-containing proteinogenic amino acids
R van Onselen, C Kennedy, TG Downing - Environmental Toxicology and …, 2024 - Elsevier
Abstract β-N-methylamino-l-alanine (BMAA) has been shown to inhibit vesicular monoamine
transporter 2 (VMAT2), thereby preventing the uptake of monoaminergic neurotransmitters …
transporter 2 (VMAT2), thereby preventing the uptake of monoaminergic neurotransmitters …
The mechanisms and modes of BMAA neurotoxicity
TG Downing, R van Onselen - Handbook of Neurotoxicity, 2021 - Springer
The hypothetical role of BMAA in lytico-bodig, the local term on Guam for what later became
known as ALS/PDC, was based on the isolation of the amino acid from common dietary …
known as ALS/PDC, was based on the isolation of the amino acid from common dietary …
Étude in vitro des effets neurotoxiques et neuro-inflammatoires de trois toxiques environnementaux analogues d'acides aminés sur des modèles de culture de cellules …
S Méresse - 2023 - theses.hal.science
Les polluants environnementaux, comme le glyphosate (GLY) et le glufosinate d'ammonium
(GLA) sont des herbicides qui participent à l'eutrophisation des milieux. Cela conduit, en …
(GLA) sont des herbicides qui participent à l'eutrophisation des milieux. Cela conduit, en …
[HTML][HTML] ALS-like disorders of the Western Pacific
B Stewart - medlink.com
Following World War II, extremely high rates of a neurodegenerative disease with features of
amyotrophic lateral sclerosis, dementia, and Parkinson disease were described in the …
amyotrophic lateral sclerosis, dementia, and Parkinson disease were described in the …