Targeting cyclooxygenases-1 and-2 in neuroinflammation: Therapeutic implications

S Aïd, F Bosetti - Biochimie, 2011 - Elsevier
Neuroinflammation has been implicated in the pathogenesis or the progression of a variety
of acute and chronic neurological and neurodegenerative disorders, including Alzheimer's …

NSAID-associated small intestinal injury: an overview from animal model development to pathogenesis, treatment, and prevention

M Zhang, F Xia, S Xia, W Zhou, Y Zhang… - Frontiers in …, 2022 - frontiersin.org
With the wide application of non-steroidal anti-inflammatory drugs (NSAIDs), their
gastrointestinal side effects are an urgent health burden. There are currently sound …

[PDF][PDF] Gastrointestinal safety of novel nonsteroidal antiinflammatory drugs: selective COX-2 inhibitors and beyond

G Coruzzi, N Venturi, S Spaggiari - Acta Biomedica-Ateneo …, 2007 - researchgate.net
Nonsteroidal antiinflammatory drugs (NSAIDs) are frequently associated with adverse
reactions, related to inhibition of cyclooxygenase (COX) in tissues where prostaglandins …

[PDF][PDF] Non-steroidal anti-inflammatory drugs target the pro-tumorigenic extracellular matrix of the postpartum mammary gland

J O'Brien, K Hansen, D Barkan, J Green… - International Journal …, 2011 - researchgate.net
Breast cancer patients diagnosed postpartum have poor prognosis. The postpartum
mammary gland undergoes tissue regression to return to the pre-pregnant state. This …

Role of coxibs in the strategies for gastrointestinal protection in patients requiring chronic non-steroidal anti-inflammatory therapy

C Blandizzi, M Tuccori, R Colucci, M Fornai… - Pharmacological …, 2009 - Elsevier
Non-steroidal anti-inflammatory drugs (NSAIDs) are among the most commonly prescribed
drugs due to their high efficacy in the treatment of pain, fever, inflammation and rheumatic …

Preparation and evaluation of celecoxib-loaded proliposomes with high lipid content

D Jeon, KT Kim, MJ Baek, DH Kim, JY Lee… - European journal of …, 2019 - Elsevier
A novel proliposomal formulation for improved oral delivery of celecoxib (CXB) was
developed using a solid dispersion technique. CXB, soy phosphatidylcholine (SPC) …

Энтеропатия, индуцированная нестероидными противовоспалительными препаратами (патогенез, диагностика, лечение)

ЯМ Вахрушев, ЕА Загребина - Терапевтический архив, 2012 - elibrary.ru
Нестероидные противовоспалительные препараты (НПВП) относятся к числу
наиболее часто используемых лекарственных средств. Важной проблемой у больных …

[HTML][HTML] Deleterious effects of indomethacin in the mid-gestation human intestine

N Perron, E Tremblay, E Ferretti, C Babakissa… - Genomics, 2013 - Elsevier
The use of the anti-inflammatory drug indomethacin (INDO) in preterm infants has been
associated with an increased risk of developing enteropathies. In this study, we have …

Diazoxide attenuates indomethacin-induced small intestinal damage in the rat

A Menozzi, C Pozzoli, E Poli, B Passeri… - European journal of …, 2011 - Elsevier
ATP-sensitive potassium (KATP) channel openers have been shown to protect against
cellular damage in neurons, cardiac muscle, and kidney and to effectively reduce …

Short-term administration of non-selective and selective COX-2 NSAIDs do not interfere with bone repair in rats

MA Matsumoto, A De Oliveira… - Journal of Molecular …, 2008 - Springer
Selective cyclooxygenase-2 non-steroidal anti-inflammatory drugs are known to inhibit bone
repair, especially when long-term administration is required due to chronicle inflammatory …