Branched chain amino acids (BCAAs), including leucine (Leu), isoleucine (Ile), and valine
(Val), play critical roles in the regulation of energy homeostasis, nutrition metabolism, gut …

Personalization of ICU nutrition is essential to future of critical care. Recommendations from
American/European guidelines and practice suggestions incorporating recent literature are …

Background Loss of skeletal muscle mass and muscle weakness are common in a variety of
clinical conditions with both wasting and weakness associated with an impairment of …

Increased understanding of metabolic derangements during critical illness provides new
potential targets for treatment. The potential of dietary protein to attenuate the muscle protein …

Background Protein ingestion increases muscle protein synthesis rates. However, limited
data are currently available on the effects of branched-chain amino acid (BCAA) and …

The compound β‐hydroxy‐β‐methyl butyrate (HMB) is proposed to increase or mitigate the
loss of skeletal muscle and improve muscle function. We undertook a review of systematic …

Objectives Supplementation of high protein oral nutrition shakes supplemented with β-
hydroxy-β-methylbutyrate (HP-HMB) has been shown to improve muscle mass, muscle …

Branched chain amino acids (BCAAs) are involved in various bioprocess such as protein
metabolism, gene expression, insulin resistance and proliferation of hepatocytes. BCAAs …

Cachexia is one of the most common, related factors of malnutrition in cancer patients.
Cancer cachexia is a multifactorial syndrome characterized by persistent loss of skeletal …

Preserving skeletal muscle mass and functional capacity is essential for healthy ageing.
Transient periods of disuse and/or inactivity in combination with sub-optimal dietary intake …