Malaria is a devastating infectious disease that is caused by blood-borne apicomplexan
parasites of the genus Plasmodium. These pathogens have a complex lifecycle, which …

Malaria remains a major cause of morbidity and mortality in the tropics, with Plasmodium
falciparum responsible for the majority of the disease burden and P. vivax being the …

Proliferation and differentiation inside erythrocytes are important steps in the life cycle of
Plasmodium spp. To achieve these, the parasites export polypeptides to the surface of …

Understanding transmission biology at an individual level is a key component of intervention
strategies that target the spread of malaria parasites from human to mosquito. Gametocytes …

Plasmodium falciparum is the major cause of malaria globally and is transmitted by
mosquitoes. During parasitic development, P. falciparum–infected erythrocytes (P …

Plasmodium falciparum, the causative agent of malaria, completely remodels the infected
human erythrocyte to acquire nutrients and to evade the immune system. For this process …

Achievement of malaria elimination requires development of novel strategies interfering with
parasite transmission, including targeting the parasite sexual stages (gametocytes). The …

Differentiation from asexual blood stages to mature sexual gametocytes is required for the
transmission of malaria parasites. Here, we report that the ApiAP2 transcription factor, PfAP2 …

Malaria is a major public health problem in many developing countries, with the malignant
tertian parasite Plasmodium falciparum causing the most malaria-associated mortality …

Plasmodium falciparum employs antigenic variation to evade the human immune response
by switching the expression of different variant surface antigens encoded by the var gene …