Chemokines play well established roles as attractants of naïve and effector T cells. New
studies indicate that chemokines also have roles in regulating T cell differentiation. Blocking …

The word chemokine is a combination of the words chemotactic and cytokine, in other words
cytokines that promote chemotaxis. Hence, the term chemokine receptor refers largely to the …

Monocyte-derived dendritic cells (DCs) and macrophages (Mϕs) generated in vitro from the
same individual blood donors were exposed to 5 different pathogens, and gene expression …

Rheumatoid arthritis (RA) is characterized by proliferation of synoviocytes that produce
inflammatory cytokines and chemokines. The expressed chemokines are thought to be …

Stromal cell-derived factor (SDF)-1 is a chemoattractant for T cells, precursor B cells,
monocytes, and neutrophils. SDF-1α was also found to up-regulate expression of early …

Background While several systemic immunomodulatory effects of allergen‐specific
immunotherapy (AIT) have been discovered, local anti‐inflammatory mechanisms in the …

Recent studies suggest that immune-modulating single-nucleotide polymorphisms (SNPs)
influence the risk of developing cancer-related infections. Here, we evaluated whether 36 …

Purpose This study aimed to investigate the impact of CC chemokine receptor 7 (CCR7) on
the recruitment and polarization of tumor-associated macrophages (TAMs) in oral squamous …

An aberrant T cell response to enteric bacteria is important in inflammatory bowel disease.
However, the identity of relevant microbial antigens is unknown. Here, we report the …

The cholinergic anti-inflammatory pathway plays an important role in controlling
inflammation. This study investigated the effects of varenicline, an α7 nicotinic acetylcholine …