Integrins are key regulators of communication between cells and with their
microenvironment. Eight members of the integrin superfamily recognize the tripeptide motif …

The research of integrin-targeted anticancer agents has recorded important advancements
in ingenious design of delivery systems, based either on the prodrug approach, or on …

Integrins, a diverse class of heterodimeric cell surface receptors, are key regulators of cell
structure and behaviour, affecting cell morphology, proliferation, survival and differentiation …

Engineering biomaterials with integrin‐binding activity is a very powerful approach to
promote cell adhesion, modulate cell behavior, and induce specific biological responses at …

Integrins are heterodimeric transmembrane proteins able to connect cells with the micro‐
environment. They represent a family of receptors involved in almost all the hallmarks of …

Interaction between the surface of implants and biological tissues is a key aspect of
biomaterials research. Apart from fulfilling the non-toxicity and structural requirements …

The interplay between specific integrin-mediated matrix adhesion and directional
persistence in cell migration is not well understood. Here, we characterized fibroblast …

Cisplatin occupies a crucial role in the treatment of various malignant tumors. However, its
efficacy and applicability are heavily restricted by severe systemic toxicities and drug …

The recent impact of implants on improving the human life quality has been enormous.
During the past two decades we witnessed major advancements in both material and …

Covalent conjugation of anticancer drugs to targeting carriers (eg, antibodies or small
molecules) capable of selectively binding to tumor-specific antigens, is emerging as a …