Genomic imprinting and physiological processes in mammals

V Tucci, AR Isles, G Kelsey, AC Ferguson-Smith… - Cell, 2019 - cell.com
Complex multicellular organisms, such as mammals, express two complete sets of
chromosomes per nucleus, combining the genetic material of both parents. However …

The congenital and acquired mechanisms implicated in the etiology of central precocious puberty

VN Brito, APM Canton, CE Seraphim… - Endocrine …, 2023 - academic.oup.com
The etiology of central precocious puberty (CPP) is multiple and heterogeneous, including
congenital and acquired causes that can be associated with structural or functional brain …

[HTML][HTML] Dlk1 gene expression in different Tissues of lamb

SH Masoudzadeh, MR Mohammadabadi… - Iranian Journal of …, 2020 - journals.iau.ir
Delta-like 1 homolog or pre-adipocyte factor 1 (Dlk1) is one of the most significant genes
and widely expresses all over mammal's development. Some of the functions identified for …

Effects of diets with different levels of fennel (Foeniculum vulgare) seed powder on DLK1 gene expression in brain, adipose tissue, femur muscle and rumen of …

SH Masoudzadeh, M Mohammadabadi, A Khezri… - Small Ruminant …, 2020 - Elsevier
Abstract DLK1 (protein delta homolog 1) plays an important role in production of adipocytes,
muscle development, wound healing, pancreas, liver and lung cells development and also …

Genomic imprinting, growth and maternal–fetal interactions

FC Cassidy, M Charalambous - Journal of Experimental …, 2018 - journals.biologists.com
In the 1980s, mouse nuclear transplantation experiments revealed that both male and
female parental genomes are required for successful development to term (;). This non …

Fetus-derived DLK1 is required for maternal metabolic adaptations to pregnancy and is associated with fetal growth restriction

MAM Cleaton, CL Dent, M Howard, JA Corish… - Nature …, 2016 - nature.com
Pregnancy is a state of high metabolic demand. Fasting diverts metabolism to fatty acid
oxidation, and the fasted response occurs much more rapidly in pregnant women than in …

Genomic imprinting and its effects on postnatal growth and adult metabolism

SJ Millership, M Van de Pette, DJ Withers - Cellular and Molecular Life …, 2019 - Springer
Imprinted genes display parent-of-origin-specific expression with this epigenetic system of
regulation found exclusively in therian mammals. Historically, defined imprinted gene …

Meg3 non-coding RNA expression controls imprinting by preventing transcriptional upregulation in cis

I Sanli, S Lalevée, M Cammisa, A Perrin, F Rage… - Cell reports, 2018 - cell.com
Although many long non-coding RNAs (lncRNAs) are imprinted, their roles often remain
unknown. The Dlk1-Dio3 domain expresses the lncRNA Meg3 and multiple microRNAs and …

The imprinted gene Delta like non-canonical Notch ligand 1 (Dlk1) is conserved in mammals, and serves a growth modulatory role during tissue development and …

GÁ Traustadóttir, LV Lagoni, LBS Ankerstjerne… - Cytokine & Growth …, 2019 - Elsevier
Delta like non-canonical Notch ligand 1 (Dlk1) is an imprinted gene, mainly known for its
involvement in adipogenesis, although it has been associated with many other stem …

Assisted reproduction causes placental maldevelopment and dysfunction linked to reduced fetal weight in mice

S Chen, F Sun, X Huang, X Wang, N Tang, B Zhu… - Scientific reports, 2015 - nature.com
Compelling evidence indicates that stress in utero, as manifested by low birth weight (LBW),
increases the risk of metabolic syndrome in adulthood. Singletons conceived by assisted …