Diverse immune functions of hemocyanins

CJ Coates, J Nairn - Developmental & Comparative Immunology, 2014 - Elsevier
Substantial evidence gathered recently has revealed the multiple functionalities of
hemocyanin. Contrary to previous claims that this ancient protein is involved solely in …

Mollusc N-glycosylation: structures, functions and perspectives

E Staudacher - Biomolecules, 2021 - mdpi.com
Molluscs display a sophisticated N-glycan pattern on their proteins, which is, in terms of
involved structural features, even more diverse than that of vertebrates. This review …

Antimicrobial activity of molluscan hemocyanins from Helix and Rapana snails

P Dolashka, A Dolashki, JV Beeumen… - Current …, 2016 - ingentaconnect.com
For the first time the antimicrobial activities of hemocyanins from the molluscs Rapana
venosa (RvH) and Helix aspersa (HaH) have been tested. From the hemolymph of the …

Glycosylation of hemocyanin in Litopenaeus vannamei is an antibacterial response feature

Z Zhang, F Wang, C Chen, Z Zheng, JJ Aweya… - Immunology letters, 2017 - Elsevier
Hemocyanin is an important multifunctional non-specific immune molecule. In this study, we
purified lectin binding and non-lectin binding hemocyanin from Litopenaeus vannamei using …

Antitumor Activity of Bioactive Compounds from Rapana venosa against Human Breast Cell Lines

M Petrova, Z Vlahova, M Schröder, J Todorova… - Pharmaceuticals, 2023 - mdpi.com
This study is the first report describing the promising antitumor activity of biologically active
compounds isolated from the hemolymph of marine snail Rapana venosa—a fraction with …

Cloning and characterization of a novel hemocyanin variant LvHMCV4 from shrimp Litopenaeus vannamei

X Lu, H Lu, L Guo, Z Zhang, X Zhao, M Zhong… - Fish & Shellfish …, 2015 - Elsevier
Recently, we found 3 variants of hemocyanin subunit with higher molecular weight in shrimp
Litopenaeus vannamei (Named as LvHMCV1-3). In this study, a novel L. vannamei …

Hemocyanins from Helix and Rapana Snails Exhibit in Vitro Antitumor Effects in Human Colorectal Adenocarcinoma

A Georgieva, K Todorova, I Iliev, V Dilcheva, I Vladov… - Biomedicines, 2020 - mdpi.com
Hemocyanins are oxygen-transporting glycoproteins in the hemolymph of arthropods and
mollusks that attract scientific interest with their diverse biological activities and potential …

Formulation of abalone hemocyanin with high antiviral activity and stability

NT Zanjani, F Sairi, G Marshall, MM Saksena… - European Journal of …, 2014 - Elsevier
Hemocyanin has been shown to have potential antiviral activity against herpes simplex virus
type-1. However, current liquid formulations have short shelf life and high risk of bacterial …

N-glycan structures of β-HlH subunit of Helix lucorum hemocyanin

L Velkova, P Dolashka, J Van Beeumen… - Carbohydrate …, 2017 - Elsevier
The carbohydrate structures of molluscan hemocyanins have recently received particular
interest due to their specific monosaccharide composition, as well as their …

[PDF][PDF] Cytotoxic effects of Rapana venosa hemocyanin on bladder cancer permanent cell lines

A Stenzl, A Dolashki, S Stevanovic… - Journal of US-China …, 2016 - academia.edu
The cytotoxic activities of hemocyanin from Rapana venosa and its structural subunits with
different oligosaccharide structures are studied in vitro on the bladder cancer permanent cell …