The Loxosceles genus spiders (the brown spiders) are encountered in all the continents,
and the clinical manifestations following spider bites include skin necrosis with gravitational …

Snakes, scorpions, and spiders are venomous animals that pose a threat to human health,
and severe envenomings from the bites or stings of these animals must be treated with …

Spiders and scorpions are notorious for their fearful dispositions and their ability to inject
venom into prey and predators, causing symptoms such as necrosis, paralysis, and …

Brown spiders are venomous arthropods that use their venom for predation and defense. In
humans, bites of these animals provoke injuries including dermonecrosis with gravitational …

Brown spider envenomation results in dermonecrosis with gravitational spreading
characterized by a marked inflammatory reaction and with lower prevalence of systemic …

Loxoscelism is the most important form of araneism in South America. The treatment of these
accidents uses heterologous antivenoms obtained from immunization of production animals …

Envenoming resulting from Loxosceles spider bites (loxoscelism) is a recognized public
health problem in Brazil. However, the pathophysiology of loxoscelism caused by L. similis …

Epitope identification is essential for developing effective antibodies that can detect and
neutralize bioactive proteins. Computational prediction is a valuable and time-saving …

Accidents involving Brown spiders are reported throughout the world. In the venom, the
major toxins involved in the deleterious effects are phospholipases D (PLDs). In this work …

Antivenom is currently the first-choice treatment for snakebite envenoming. However, only a
low proportion of antivenom immunoglobulins are specific to venom toxins, resulting in poor …