Chagas disease is currently endemic to 21 Latin-American countries and has also become a
global concern because of globalization and mass migration of chronically infected …

In the past ten years, studies have shown the recognition of Trypanosoma cruzi‐associated
molecular patterns by members of the Toll‐like receptor (TLR) family and demonstrated the …

In Chagas disease, CD8+ T-cells are critical for the control of Trypanosoma cruzi during
acute infection. Conversely, CD8+ T-cell accumulation in the myocardium during chronic …

Water-soluble polypeptides from pilose antler (PAWPs) are a traditional Chinese functional
food and have been reported to inhibit triple-negative breast cancer (TNBC) in mice. Thus, in …

Chagas disease (CD), caused by the protozoan Trypanosoma cruzi, is a prototypical
neglected tropical disease. Specific immunity promotes acute phase survival. Nevertheless …

Chagas disease is major public health problem, affecting nearly 10 million people,
characterized by cardiac alterations leading to congestive heart failure and death of 20-40 …

Vaccines against parasites have lagged centuries behind those against viral and bacterial
infections, despite the devastating morbidity and widespread effects of parasitic diseases …

In mammals, chronic diseases resulting from infectious agents have been associated with
functional T cell response deficiency, a high frequency of terminally differentiated T cells, the …

Chagas disease (CD) treatment and vaccine development are critical due to the significant
health burden caused by the disease, especially in Latin America. Current treatments …

Chagas' disease is a major public health problem affecting nearly 10 million in Latin
America. Despite several experimental vaccines have shown to be immunogenic and …