Benzoannelated heterocycles such as benzodiazepines and indoles can be prepared
efficiently through cyclization on solid supports, although no single approach is currently …

Initiation, progression, and completion of the cell cycle are regulated by various cyclin-
dependent kinases (CDKs), which are thus critical for cell growth. Tumour development is …

A novel visible-light-promoted selective sulfonylation and selenylation of dienes with
selenosulfonates has been developed. This technology provides mild access to a wide …

Paullones constitute a new family of benzazepinones with promising antitumoral properties.
They were recently described as potent, ATP‐competitive, inhibitors of the cell cycle …

A new Rh (III)-catalyzed aldehydic CH activation/[4+ 3] annulation cascade of N-sulfonyl-2-
aminobenzaldehydes with gem-difluorocyclopropenes is reported for the first time, and used …

Cancer is associated with uncontrolled cell proliferation invading adjoining tissues and
organs. Despite the availability of several chemotherapeutic agents, the constant search for …

A synthesis of azepines by the expansion of pyridine rings promoted by iodine in air is
reported. The scope of the method is demonstrated with 27 examples. Two iodinations are …

Hymenialdisine an alkaloid of oroidin class has drawn the attention of researchers owing to
its unique structural features and interesting biological properties. Hymenialdisine exhibited …

Novel hybrids of pyridazine-pyrazoline were synthesized aiming to develop new
antiproliferative candidates. All compounds were submitted to the National Cancer Institute …

Benzo [b] azepines are important structural motifs for the pharmaceutical industry. However,
their syntheses are usually lengthy, involving several steps, transition-metal catalysts, and/or …