Liposomes: Structure, composition, types, and clinical applications

H Nsairat, D Khater, U Sayed, F Odeh, A Al Bawab… - Heliyon, 2022 - cell.com
Liposomes are now considered the most commonly used nanocarriers for various potentially
active hydrophobic and hydrophilic molecules due to their high biocompatibility …

Smart materials for drug delivery and cancer therapy

Y Yang, W Zeng, P Huang, X Zeng, L Mei - View, 2021 - Wiley Online Library
Until now, enormous smart materials have been engineered with endogenous stimulators
such as pH, reactive oxygen species, glutathione, hypoxia and enzyme, or exogenous …

Smart chemistry-based nanosized drug delivery systems for systemic applications: a comprehensive review

T Ramasamy, HB Ruttala, B Gupta, BK Poudel… - Journal of Controlled …, 2017 - Elsevier
This review focuses on the smart chemistry that has been utilized in developing polymer-
based drug delivery systems over the past 10 years. We provide a comprehensive overview …

Mechanisms of drug release in nanotherapeutic delivery systems

PT Wong, SK Choi - Chemical reviews, 2015 - ACS Publications
Targeted drug delivery refers to an established therapeutic strategy that develops platforms
and nanoscale devices for selective delivery of small drug molecules and therapeutic genes …

Most mammalian mRNAs are conserved targets of microRNAs

RC Friedman, KKH Farh, CB Burge… - Genome research, 2009 - genome.cshlp.org
MicroRNAs (miRNAs) are small endogenous RNAs that pair to sites in mRNAs to direct post-
transcriptional repression. Many sites that match the miRNA seed (nucleotides 2–7) …

Multistage nanoparticle delivery system for deep penetration into tumor tissue

C Wong, T Stylianopoulos, J Cui… - Proceedings of the …, 2011 - National Acad Sciences
Current Food and Drug Administration-approved cancer nanotherapeutics, which passively
accumulate around leaky regions of the tumor vasculature because of an enhanced …

Polymer nanogels: a versatile nanoscopic drug delivery platform

RT Chacko, J Ventura, J Zhuang… - Advanced drug delivery …, 2012 - Elsevier
In this review we put the spotlight on crosslinked polymer nanogels, a promising platform
that has the characteristics of an “ideal” drug delivery vehicle. Some of the key aspects of …

A review of drug release mechanisms from nanocarrier systems

C Ding, Z Li - Materials Science and Engineering: C, 2017 - Elsevier
The most common methods used for drug administrations are pills, injections, lotions and
suppositories. The preferred means is oral dosage forms as it is simple, painless and self …

Polymer–drug conjugates: progress in polymeric prodrugs

J Khandare, T Minko - Progress in polymer science, 2006 - Elsevier
Polymers are used as carriers for the delivery of drugs, proteins, targeting moieties, and
imaging agents. Several polymers, poly (ethylene glycol)(PEG), N-(2-hydroxypropyl) …

Extracellularly activated nanocarriers: a new paradigm of tumor targeted drug delivery

E Gullotti, Y Yeo - Molecular pharmaceutics, 2009 - ACS Publications
One of the main goals of nanomedicine is to develop a nanocarrier that can selectively
deliver anticancer drugs to the targeted tumors. Extensive efforts have resulted in several …