Y Yang, W Zeng, P Huang, X Zeng, L Mei - View, 2021 - Wiley Online Library
Until now, enormous smart materials have been engineered with endogenous stimulators such as pH, reactive oxygen species, glutathione, hypoxia and enzyme, or exogenous …
This review focuses on the smart chemistry that has been utilized in developing polymer- based drug delivery systems over the past 10 years. We provide a comprehensive overview …
PT Wong, SK Choi - Chemical reviews, 2015 - ACS Publications
Targeted drug delivery refers to an established therapeutic strategy that develops platforms and nanoscale devices for selective delivery of small drug molecules and therapeutic genes …
MicroRNAs (miRNAs) are small endogenous RNAs that pair to sites in mRNAs to direct post- transcriptional repression. Many sites that match the miRNA seed (nucleotides 2–7) …
Current Food and Drug Administration-approved cancer nanotherapeutics, which passively accumulate around leaky regions of the tumor vasculature because of an enhanced …
In this review we put the spotlight on crosslinked polymer nanogels, a promising platform that has the characteristics of an “ideal” drug delivery vehicle. Some of the key aspects of …
C Ding, Z Li - Materials Science and Engineering: C, 2017 - Elsevier
The most common methods used for drug administrations are pills, injections, lotions and suppositories. The preferred means is oral dosage forms as it is simple, painless and self …
Polymers are used as carriers for the delivery of drugs, proteins, targeting moieties, and imaging agents. Several polymers, poly (ethylene glycol)(PEG), N-(2-hydroxypropyl) …
E Gullotti, Y Yeo - Molecular pharmaceutics, 2009 - ACS Publications
One of the main goals of nanomedicine is to develop a nanocarrier that can selectively deliver anticancer drugs to the targeted tumors. Extensive efforts have resulted in several …