Sepsis is a common consequence of infection, associated with a mortality rate> 25%.
Although community-acquired sepsis is more common, hospital-acquired infection is more …

Severe or life threatening infections are common among patients in the intensive care unit
(ICU). Most infections in the ICU are bacterial or fungal in origin and require antimicrobial …

Objectives Candidaemia is a serious hazard to hospitalized patients, but European
epidemiological data are restricted to national studies focusing on Northern Europe …

Invasive candidiasis is the most common critical care-associated fungal infection with a
crude mortality of~ 40–55%. Important factors contributing to risk of invasive candidiasis in …

Background Antimicrobial de-escalation (ADE) is a strategy of antimicrobial stewardship,
aiming at preventing the emergence of antimicrobial resistance (AMR) by decreasing the …

Introduction The term invasive candidiasis (IC) refers to both bloodstream and deep-seated
invasive infections, such as peritonitis, caused by Candida species. Several guidelines on …

Background Despite advances in the management of bloodstream infections (BSI) caused
by Candida spp., the mortality still remains high in critically ill patients. The worldwide …

Patients with haematological malignancies, haemopoietic stem cell transplant recipients and
patients requiring admission to intensive care settings are at high risk for invasive …

Candidemia is the fourth most frequent health care-associated bloodstream infection, and
the most frequent severe fungal infection developing in critically ill patients in intensive care …

Candida glabrata bloodstream infection (BSI) isolates from a particular geographic area
have been reported to comprise a relatively small number of the major sequence types (STs) …