Studying the interaction of drug/ligand with serum albumin
S Siddiqui, F Ameen, S ur Rehman, T Sarwar… - Journal of Molecular …, 2021 - Elsevier
The interaction between proteins and drugs/ligands has been explored thoroughly over the
past years. Numerous spectroscopic and in silico tools are employed to decipher the binding …
past years. Numerous spectroscopic and in silico tools are employed to decipher the binding …
Protein misfolding, aggregation and mechanism of amyloid cytotoxicity: An overview and therapeutic strategies to inhibit aggregation
Protein and peptides are converted from their soluble forms into highly ordered fibrillar
aggregates under various conditions inside the cell. Such transitions confer diverse …
aggregates under various conditions inside the cell. Such transitions confer diverse …
Insights into the effect of glucose on the binding between human serum albumin and the nonsteroidal anti-inflammatory drug nimesulide
MAG Soares, PA de Aquino, T Costa, C Serpa… - International Journal of …, 2024 - Elsevier
Glucose interacts with human serum albumin (HSA, the main protein responsible for the
biodistribution of drugs in the bloodstream) and consequently affects the binding capacity of …
biodistribution of drugs in the bloodstream) and consequently affects the binding capacity of …
A comprehensive spectroscopic and computational investigation on the binding of the anti-asthmatic drug triamcinolone with serum albumin
S Siddiqui, F Ameen, I Jahan, SM Nayeem… - New Journal of …, 2019 - pubs.rsc.org
The biomolecular interaction of triamcinolone with bovine serum albumin (BSA) was studied
using various multi-spectroscopic techniques in combination with in silico studies. UV-visible …
using various multi-spectroscopic techniques in combination with in silico studies. UV-visible …
Investigating the site selective binding of busulfan to human serum albumin: Biophysical and molecular docking approaches
We have studied the binding of busulfan (BN) to human serum albumin (HSA) at
physiological pH 7.4 by using fluorescence, UV–vis and circular dichroism (CD) …
physiological pH 7.4 by using fluorescence, UV–vis and circular dichroism (CD) …
Understanding the impacts of molecular and macromolecular crowding agents on protein–polymer complex coacervates
Complex coacervation refers to the liquid–liquid phase separation (LLPS) process occurring
between charged macromolecules. The study of complex coacervation is of great interest …
between charged macromolecules. The study of complex coacervation is of great interest …
Exploring the interactions of a Tb (III)–quercetin complex with serum albumins (HSA and BSA): spectroscopic and molecular docking studies
M Shaghaghi, S Rashtbari, S Vejdani… - …, 2020 - Wiley Online Library
Serum albumins (human serum albumin (HSA) and bovine serum albumin (BSA), two main
circulatory proteins), are globular and monomeric macromolecules in plasma that transport …
circulatory proteins), are globular and monomeric macromolecules in plasma that transport …
Anti-amyloidogenic behavior and interaction of diallylsulfide with human serum albumin
In this work, binding of garlic component-Diallysulfide (DAS) with major human blood
transport protein, Human Serum Albumin (HSA) and its anti-amyloidogenic behavior has …
transport protein, Human Serum Albumin (HSA) and its anti-amyloidogenic behavior has …
Effects of Heme site (FA1) ligands bilirubin, biliverdin, hemin, and methyl orange on the albumin binding of site I marker warfarin: complex allosteric interactions
Human serum albumin (HSA) is the most abundant plasma protein in circulation. The three
most important drug-binding sites on HSA are Sudlow's Site I (subdomain IIA), Sudlow's Site …
most important drug-binding sites on HSA are Sudlow's Site I (subdomain IIA), Sudlow's Site …
Amyloid-like aggregation of bovine serum albumin at physiological temperature induced by cross-seeding effect of HEWL amyloid aggregates
S Nirwal, V Bharathi, BK Patel - Biophysical Chemistry, 2021 - Elsevier
BSA can form amyloid-like aggregates in vitro at 65° C. Heterologous amyloid can
proposedly cross-seed other protein's aggregation, however, general mechanisms and …
proposedly cross-seed other protein's aggregation, however, general mechanisms and …