Aptamer-based diagnostic systems for the rapid screening of TB at the point-of-care

DR Martin, NR Sibuyi, P Dube, AO Fadaka, R Cloete… - Diagnostics, 2021 - mdpi.com
The transmission of Tuberculosis (TB) is very rapid and the burden it places on health care
systems is felt globally. The effective management and prevention of this disease requires …

Diagnostic accuracy of commercial urinary lipoarabinomannan detection in African tuberculosis suspects and patients

R Mutetwa, C Boehme, M Dimairo… - … of Tuberculosis and …, 2009 - ingentaconnect.com
OBJECTIVE: To evaluate a commercially available antigen capture enzyme-linked
immunosorbent assay (ELISA) based on detecting lipoarabinomannan (LAM) in urine for the …

Utility of broad-spectrum antibiotics for diagnosing pulmonary tuberculosis in adults: a systematic review and meta-analysis

TH Divala, KL Fielding, C Kandulu… - The Lancet Infectious …, 2020 - thelancet.com
Background Suboptimal diagnostics for pulmonary tuberculosis drive the use of the so-
called trial of antibiotics, a course of broad-spectrum antibiotics without activity against …

Sensitivity and specificity of routine diagnostic work-up for tuberculosis in lung clinics in Yogyakarta, Indonesia: a cohort study

AMI Saktiawati, YW Subronto, Y Stienstra, Sumardi… - BMC Public Health, 2019 - Springer
Background Establishing a correct diagnosis is challenging. We aimed to investigate the
sensitivity and specificity of routine tuberculosis (TB) diagnostic work-up in lung clinics in …

The effect of HIV and antiretroviral therapy on characteristics of pulmonary tuberculosis in northern Malawi: a cross-sectional study

L Munthali, PY Khan, NJ Mwaungulu, F Chilongo… - BMC infectious …, 2014 - Springer
Background HIV infection reduces the likelihood that individuals with pulmonary
tuberculosis are smear positive and that they have cavitatory disease. Antiretroviral therapy …

Performance of the 2007 WHO algorithm to diagnose smear-negative pulmonary tuberculosis in a HIV prevalent setting

H Huerga, F Varaine, E Okwaro, M Bastard… - PloS one, 2012 - journals.plos.org
Background The 2007 WHO algorithm for diagnosis of smear-negative pulmonary
tuberculosis (PTB) including Mycobacterium tuberculosis (MTB) culture was evaluated in a …

Cost-effectiveness analysis of the Xpert MTB/RIF assay for rapid diagnosis of suspected tuberculosis in an intermediate burden area

JHS You, G Lui, KM Kam, NLS Lee - Journal of Infection, 2015 - Elsevier
Objectives We examined, from a Hong Kong healthcare providers' perspective, the cost-
effectiveness of rapid diagnosis with Xpert in patients hospitalized for suspected active …

Screening for active pulmonary tuberculosis: Development and applicability of artificial neural network models

JBO e Souza, M Sanchez, JM de Seixas… - Tuberculosis, 2018 - Elsevier
Tuberculosis (TB) remains a significant public health challenge, motivated by the diversity of
healthcare epidemiological settings, as other factors. Cost-effective screening has …

[HTML][HTML] A screening system for smear-negative pulmonary tuberculosis using artificial neural networks

JBO Souza Filho, JM de Seixas, R Galliez… - International Journal of …, 2016 - Elsevier
Objectives Molecular tests show low sensitivity for smear-negative pulmonary tuberculosis
(PTB). A screening and risk assessment system for smear-negative PTB using artificial …

Predictors of smear-negative pulmonary tuberculosis in HIV-infected patients, Battambang, Cambodia

A Tamhane, P Chheng, T Dobbs, S Mak… - … of tuberculosis and …, 2009 - ingentaconnect.com
DESIGN: Retrospective data analysis of human immunodeficiency virus (HIV) infected
patients attending an HIV clinic (referral hospital), Cambodia. Chest X-rays (CXRs) were …