The progress of precision medicine research hinges on the gathering and analysis of
extensive and diverse clinical datasets. With the continued expansion of modalities, scales …

Aggressive natural killer cell leukemia (ANKL) is a rare hematological malignancy with a
fulminant clinical course. Our previous study revealed that ANKL cells proliferate …

DNA changes that cause premature termination codons (PTCs) represent a large fraction of
clinically relevant pathogenic genomic variation. Typically, PTCs induce transcript …

Protein lysine acetylation is a critical post-translation modification (PTM) involved in a wide
range of biological processes. To date, about 20,000 acetylation sites of Homo sapiens were …

Dicrocoelium lancet flukes cause significant production loss in ruminant livestock. Although
co-infection with multiple Dicrocoelium species within a host is common, techniques for …

Kirrel3 is a cell-adhesion molecule that instructs the formation of specific synapses during
brain development in mouse and Kirrel3 variants may be risk factors for autism and …

Hypoplastic left heart syndrome (HLHS) is a congenital heart disease where the left ventricle
is reduced in size. A forward genetic screen in mice identified SIN3A associated protein 130 …

The expeditious identification and comprehensive analysis of clonal families from extensive
B cell receptor (BCR) repertoire sequencing data are imperative for elucidating the …

RNA expression levels are controlled by the complementary processes of synthesis and
degradation. Although mis-regulation of RNA turnover is linked to neurodevelopmental …

Honeybee, positioned as an outgroup of flies and mosquitos, have exhibited intriguing
duplications and expansions of OR genes in genomic studies. However, little is known about …