[HTML][HTML] Anticoagulants: a short history, their mechanism of action, pharmacology, and indications

M Heestermans, G Poenou, H Hamzeh-Cognasse… - Cells, 2022 - mdpi.com
Anticoagulant drugs antagonize coagulation and are used to prevent or cure (recurrent)
venous thromboembolism (VTE). Drugs to prevent clotting have been used for more than a …

[HTML][HTML] Risk and management of bleeding complications with direct oral anticoagulants in patients with atrial fibrillation and venous thromboembolism: a narrative …

S Ballestri, E Romagnoli, D Arioli, V Coluccio… - Advances in …, 2023 - Springer
Atrial fibrillation (AF) and venous thromboembolism (VTE) are highly prevalent conditions
with a significant healthcare burden, and represent the main indications for anticoagulation …

Factor XI inhibition for the prevention of venous thromboembolism: an update on current evidence and future perspectives

G Poenou, T Dumitru Dumitru, L Lafaie… - Vascular Health and …, 2022 - Taylor & Francis
During the past decade, emergence of direct oral anticoagulants (DOACs) has drastically
improved the prevention of thrombosis. However, several unmet needs prevail in the field of …

Anticoagulation and venous thromboembolism in patients aged 90 years and older: Data from the RIETE registry

L Lafaie, G Poenou, O Hanon… - Journal of the …, 2024 - Wiley Online Library
Background Age is a major risk factor for venous thromboembolism (VTE), yet patients
aged≥ 90 years are under‐represented in clinical trials of anticoagulant therapy. The …

Association of type of oral anticoagulation with risk of bleeding in 45,114 patients with venous thromboembolism during initial and extended treatment—A nationwide …

K Glise Sandblad, S Schulman… - Journal of Internal …, 2023 - Wiley Online Library
Background Safety data for different anticoagulant medications in venous thromboembolism
(VTE) are scarce, in particular for extended treatment. Objectives To compare major …

[HTML][HTML] Clinical impact of high platelet reactivity in patients with atrial fibrillation and concomitant percutaneous coronary intervention on dual or triple antithrombotic …

M Berteotti, AM Gori, B Giusti, A Fortini, G Grossi… - Journal of Thrombosis …, 2023 - Springer
High platelet reactivity (HPR) on clopidogrel is an established thrombotic risk factor after
percutaneous coronary intervention (PCI). The introduction of more potent antiplatelet drugs …

[HTML][HTML] Low molecular weight heparin treatment patterns and outcomes in cancer patients with acute venous thromboembolism: a nationwide cohort study in France

L Bertoletti, G Gusto, N Quignot, A Khachatryan… - Cancers, 2023 - mdpi.com
Simple Summary Venous thromboembolism (VTE) is a common and often fatal complication
in cancer patients. The initial treatment for VTE in cancer patients is typically low molecular …

Patterns and persistence of anticoagulant use in the treatment of venous thromboembolism: insights from South Korea

F Germini, NC Chan - Thrombosis and Haemostasis, 2024 - thieme-connect.com
When used in fixed doses for the treatment of venous thromboembolism (VTE) in patients
with or without cancer, direct oral anticoagulants (DOACs) have improved risk–benefit …

Comparison of Effectiveness and Safety Among 3 Direct Oral Anticoagulants in Patients With Venous Thromboembolism―A Single-Center Retrospective Study―

Y Ueno, S Ikeda, T Motokawa, T Honda… - Circulation …, 2022 - jstage.jst.go.jp
Background: Direct oral anticoagulants (DOACs), including edoxaban, rivaroxaban, and
apixaban, are administered for the treatment of venous thromboembolism (VTE) in Japan …

Efficacy and safety of direct oral anticoagulants versus warfarin in the treatment of cerebral venous sinus thrombosis

E Sadeghi Hokmabadi, A Daei Sorkhabi… - Acta Neurologica …, 2024 - Springer
Background Given the evolving application and promising outcomes of direct oral
anticoagulants (DOACs) in various thromboembolic conditions, we aimed to compare the …