Multiple sclerosis (MS) is an inflammatory demyelinating disease of the central nervous
system (CNS) where immunopathology is thought to be mediated by myelin-reactive CD4+ T …

Helper T (Th) cells secret specific cytokines that promote immune responses whereas
glucocorticoids limit the extent of immune responses by inhibiting cytokine secretion and …

Objectives We explored whether genetically predicted increased body mass index (BMI)
modulates multiple sclerosis (MS) risk through interleukin-6 (IL-6) signaling. Methods We …

Background Glucocorticoid resistance has been associated with Th17‐driven inflammation,
the mechanisms of which are not clear. We determined whether human and mouse Th17 …

To identify genes and biologically relevant pathways associated with risk to develop multiple
sclerosis (MS), the Genome-Wide Association Studies noise reduction method (GWAS-NR) …

Objective To assess the effects of dietary vitamin D3 on proinflammatory (interleukin-17A [IL-
17A] and IL-6) and anti-inflammatory (IL-10) cytokines. Methods Our study was conducted …

Depression is a severe mental disorder that disrupts mood and social behavior and is one of
the most common neuropsychological symptoms of other somatic diseases. During the study …

Th17 cells contribute to several inflammatory conditions and increasing evidence supports
that Th17 cells are glucocorticoid resistant. However, Th17 cells in psoriasis and related …

Elevated frequency of Th17‐like cells expressing Toll‐like receptors (TLRs) has been
recently associated with relapsing–remitting multiple sclerosis (MS) pathogenesis, a chronic …

Rheumatoid arthritis (RA) is a chronic autoimmune disease which is characterized by
synovial inflammation and cartilage damage for which causes articular dysfunction …