Neurotrophin regulation of neural circuit development and function

H Park, M Poo - Nature Reviews Neuroscience, 2013 - nature.com
Brain-derived neurotrophic factor (BDNF)—a member of a small family of secreted proteins
that includes nerve growth factor, neurotrophin 3 and neurotrophin 4—has emerged as a …

On the neuroprotective role of astaxanthin: new perspectives?

C Galasso, I Orefice, P Pellone, P Cirino, R Miele… - Marine drugs, 2018 - mdpi.com
Astaxanthin is a carotenoid with powerful antioxidant and anti-inflammatory activity
produced by several freshwater and marine microorganisms, including bacteria, yeast, fungi …

Multipotent CNS stem cells are present in the adult mammalian spinal cord and ventricular neuroaxis

S Weiss, C Dunne, J Hewson, C Wohl… - Journal of …, 1996 - Soc Neuroscience
Neural stem cells in the lateral ventricles of the adult mouse CNS participate in repopulation
of forebrain structures in vivo and are amenable to in vitro expansion by epidermal growth …

Inducible and constitutive transcription factors in the mammalian nervous system: control of gene expression by Jun, Fos and Krox, and CREB/ATF proteins

T Herdegen, JD Leah - Brain research reviews, 1998 - Elsevier
This article reviews findings up to the end of 1997 about the inducible transcription factors
(ITFs) c-Jun, JunB, JunD, c-Fos, FosB, Fra-1, Fra-2, Krox-20 (Egr-2) and Krox-24 (NGFI-A …

Adult brain neurogenesis and psychiatry: a novel theory of depression

BL Jacobs, H Van Praag, FH Gage - Molecular psychiatry, 2000 - nature.com
Neurogenesis (the birth of new neurons) continues postnatally and into adulthood in the
brains of many animal species, including humans. This is particularly prominent in the …

Adult neurogenesis: from precursors to network and physiology

DN Abrous, M Koehl, M Le Moal - Physiological reviews, 2005 - journals.physiology.org
The discovery that the adult mammalian brain creates new neurons from pools of stemlike
cells was a breakthrough in neuroscience. Interestingly, this particular new form of structural …

[HTML][HTML] BDNF regulates eating behavior and locomotor activity in mice

SG Kernie, DJ Liebl, LF Parada - The EMBO journal, 2000 - embopress.org
Brain‐derived neurotrophic factor (BDNF) was studied initially for its role in sensory neuron
development. Ablation of this gene in mice leads to death shortly after birth, and …

The impact of maternal high-fat diet on offspring neurodevelopment

G Urbonaite, A Knyzeliene, FS Bunn… - Frontiers in …, 2022 - frontiersin.org
A maternal high-fat diet affects offspring neurodevelopment with long-term consequences on
their brain health and behavior. During the past three decades, obesity has rapidly …

Knockdown of brain-derived neurotrophic factor in specific brain sites precipitates behaviors associated with depression and reduces neurogenesis

D Taliaz, N Stall, DE Dar, A Zangen - Molecular psychiatry, 2010 - nature.com
Depression has been associated with reduced expression of brain-derived neurotrophic
factor (BDNF) in the hippocampus. In addition, animal studies suggest an association …

The therapeutic potential of neural stem cells

G Martino, S Pluchino - Nature Reviews Neuroscience, 2006 - nature.com
Recent evidence shows that transplantation of neural stem/precursor cells may protect the
central nervous system from inflammatory damage through a'bystander'mechanism that is …