An update on benzofuran inhibitors: a patent review

KM Dawood - Expert Opinion on Therapeutic Patents, 2019 - Taylor & Francis
Introduction: Benzofuran is a fundamental unit in numerous bioactive heterocycles. They
have attracted chemists and medical researchers due to their broad range of biological …

Recent advances in the synthetic chemistry of 1, 5‐benzothiazepines: A minireview

V Devi, G Singh, V Monga - Journal of Heterocyclic Chemistry, 2020 - Wiley Online Library
Benzothiazepine, a prominent “drug prejudice core”, is a heterocyclic moiety of immense
importance due to its presence in a wide range of bioactive compounds. They act as a …

Therapeutic potential of naturally occurring benzofuran derivatives and hybrids of benzofurans with other pharmacophores as antibacterial agents

Z Xu, D Xu, W Zhou, X Zhang - Current Topics in Medicinal …, 2022 - ingentaconnect.com
Gram-positive and Gram-negative pathogens are able to evade the host immune system,
persist within the human host, and lead to severe disease and even death. At present …

Chemistry and pharmacological diversity of benzothiazepine—Excellent pathway to drug discovery

TA Ogunnupebi, OO Ajani, GO Oduselu… - Journal of molecular …, 2023 - Elsevier
In this era of sporadic advancement in science and technology, a substantial amount of
intervention is being set in motion to reduce health-related diseases. Discoveries from …

Five-membered ring systems: furans and benzofurans

H Kwiecień, A Wodnicka - Progress in Heterocyclic Chemistry, 2020 - Elsevier
Furans and their benzo-fused derivatives possess a diverse set of properties that allow a
wide range of applications, spanning from medicinal chemistry to photo-and …

Synthesis, characterization, in vitro cholinesterase and hRBCs hemolysis assay and computational evaluation of novel 2, 3, 4, 5-tetrahydrobenzothiazepine appended …

S Shaikh, P Dhavan, J Uparkar, P Singh, SP Vaidya… - Bioorganic …, 2021 - Elsevier
Abstract A series of novel 2, 3, 4, 5-tetrahydrobenzothiazepine appended α-
aminophosphonate derivatives were synthesized by subjecting 2, 3-dihydrobenzothiazepine …

Novel benzyl phenyl sulfide derivatives as antibacterial agents against methicillin-resistant Staphylococcus aureus

K Lu, Q Chen, XF Xu, Y Meng, J Lin… - The Journal of …, 2020 - nature.com
Methicillin-resistant Staphylococcus aureus (MRSA) infection is a major threat to human
health due to its resistance to almost all classes of antibiotics. Discovery of novel …

In silico studies of benzothiazole derivatives as potential inhibitors of Anopheles funestus and Anopheles gambiae trehalase

TA Ogunnupebi, GO Oduselu, OF Elebiju… - Frontiers in …, 2024 - frontiersin.org
Introduction In malaria management, insecticides play a crucial role in targeting disease
vectors. Benzothiazole derivatives have also been reported to possess insecticidal …

Synthesis of novel fluorinated 1, 5-benzothiazepine derivatives and their biological evaluation as anticancer and antibacterial agents

SR Bhabal, SF Shaikh, IP Yellapurkar… - Journal of the Serbian …, 2022 - shd-pub.org.rs
A series of novel fluorinated 1, 5-benzothiazepine derivatives were synthesized,
characterized and evaluated for in vitro anticancer and antibacterial activity. The in vitro …

Synthesis of poly-functionalized benzofurans via one-pot domino oxidation/[3+ 2] cyclization reactions of a hydroquinone ester and ynamides

D Zhang, J Man, Y Chen, L Yin, J Zhong, QF Zhang - RSC advances, 2019 - pubs.rsc.org
Densely substituted amino-functionalized benzofurans were concisely accessed via the first
one-pot domino oxidation/[3+ 2] cyclization of a hydroquinone ester and easily accessible …