Analysis of flow field and turbulence predictions in a lung model applying RANS and implications for particle deposition

M Sommerfeld, OL Sgrott Jr, MA Taborda… - European Journal of …, 2021 - Elsevier
Airflow and aerosol deposition in the human airways are important aspects for applications
such as pulmonary drug delivery and human exposure to aerosol pollutants. Numerical …

The effect of oral and nasal breathing on the deposition of inhaled particles in upper and tracheobronchial airways

F Lizal, J Elcner, J Jedelsky, M Maly, M Jicha… - Journal of aerosol …, 2020 - Elsevier
The inhalation route has a substantial influence on the fate of inhaled particles. An outbreak
of infectious diseases such as COVID-19, influenza or tuberculosis depends on the site of …

[HTML][HTML] Numerical simulations for inhalation product development: Achievements and current limitations

A Benassi, C Cottini - ONdrugDelivery, 2021 - ondrugdelivery.com
NUMERICAL SIMULATIONS FOR INHALATION PRODUCT DEVELOPMENT:
ACHIEVEMENTS AND CURRENT LIMITATIONS - ONdrugDelivery OndrugDelivery …

The effect of the volumetric flow rate and endotracheal tube diameter on the pressure distribution in human airways

AZ Selvaggio, S Lisbôa Jr, SSV Vianna - Medical Engineering & Physics, 2021 - Elsevier
The comprehension of the fluid flow in the upper airways is of paramount importance when
treating patients under clinical conditions that demand mechanical ventilation. Barotrauma …

[PDF][PDF] Experimental and Computational Modelling of Aerosol Transport Using the BUT Benchmark Human Lung Model

F Lizal, J Elcner, M Belka, J Jedelsky, M Jicha - ERCOFTAC Bulletin, 2021 - ercoftac.org
The aerosol team at the Brno University of Technology (BUT) has continuously developed a
realistic human lung model and has used it for aerosol transport studies since 2006. The …

[PDF][PDF] NUMERICAL SIMULATIONS FOR INHALATION PRODUCT DEVELOPMENT: ACHIEVEMENTS AND CURRENT LIMITATIONS

C Cottini, I Head, C Farmaceutici, A Benassi - ondrugdelivery.com
• Harsh environments, such as hot corrosive solvents in reactors or abrasive conditions in
powder mills• Limitations imposed by quality and safety protocols in manufacturing for …