Superoxide, O2•−, is formed in all living organisms that come in contact with air, and,
depending upon its biological context, it may act as a signaling agent, a toxic species, or a …

Non-heme iron enzymes promote a number of important biological reactions, including
serotonin, 1 leukotreine, 2 and DNA3 synthesis. Most mononuclear non-heme iron enzymes …

Mononuclear iron (III) species with end-on and side-on peroxide have been proposed or
identified in the catalytic cycles of the antitumor drug bleomycin and a variety of enzymes …

Iron-peroxide intermediates are central in the reaction cycle of many iron-containing
biomolecules. We trapped iron (III)-(hydro) peroxo species in crystals of superoxide …

The Fenton or Fenton-type reaction between aqueous ferrous ion and hydrogen peroxide
generates a highly oxidizing species, most often formulated as hydroxyl radical or ferryl …

A reductive paradigm has emerged in recent years for detoxification of superoxide and other
redox active diatomic molecules in air-sensitive bacteria and archaea. Adventitiously …

Some sulfate-reducing and microaerophilic bacteria rely on the enzyme superoxide
reductase (SOR) to eliminate the toxic superoxide anion radical (O 2·−). SOR catalyses the …

Superoxide anion is among the deleterious reactive oxygen species, towards which all
organisms have specialized detoxifying enzymes. For quite a long time, superoxide …

Iron peroxide species have been identified as important intermediates in a number of
nonheme iron as well as heme-containing enzymes, yet there are only a few examples of …

For more than 30 years, the only enzymatic system known to catalyze the elimination of
superoxide was superoxide dismutase, SOD. SOD has been found in almost all organisms …