Snail1 is the founding member of the Snail superfamily of zinc-finger transcription factors,
which also includes Snail2 (Slug) and Snail3 (Smuc). The superfamily is involved in cell …

The Gleason grading system for prostate adenocarcinoma has evolved from its original
scheme established in the 1960s–1970s, to a significantly modified system after two major …

The field of prostate cancer has been the subject of extensive research that has resulted in
important discoveries and shaped our appreciation of this disease and its management …

Background Substantial geographical differences in prostate cancer (PCa) incidence and
mortality exist, being lower among Asian (ASI) men compared with Caucasian (CAU) men …

Aims: The 2005 International Society of Urological Pathology (ISUP) modification of Gleason
grading recommended that the highest grade should always be included in the Gleason …

Introduction Transcriptional analyses have identified several distinct molecular subtypes in
pancreatic ductal adenocarcinoma (PDAC) that have prognostic and potential therapeutic …

Histologic grading remains the gold standard for prognosis in prostate cancer, and
assessment of Gleason score plays a critical role in active surveillance management. We …

Background No data exist on the patterns of biochemical recurrence (BCR) and their effect
on survival in patients with high-risk prostate cancer (PCa) treated with surgery. The aim of …

Purpose To evaluate the correlation between apparent diffusion coefficient measurements
(ADCtumor and ADCratio) and the Gleason score from radical prostatectomy specimens …

Background Shear wave imaging (SWI) is a new ultrasound technique whose application
facilitates quantitative tissue elasticity assessment during transrectal ultrasound biopsies of …