The c-fos gene was first described as a proto-oncogene responsible for the induction of
bone tumors. A few decades ago, activation of the protein product c-fos was reported in the …

Circadian clocks are self-sustaining genetically based molecular machines that impose∼
24h rhythmicity on physiology and behavior that synchronize these functions with the solar …

The retina is an integral part of the central nervous system (CNS), communicating directly
with the brain via ganglion cell axons passing through the optic nerve, and is composed of …

Along evolution, living organisms developed a precise timekeeping system, circadian
clocks, to adapt life to the 24-h light/dark cycle and temporally regulate physiology and …

The mechanisms that co-ordinately activate lipid synthesis when high rates of membrane
biogenesis are needed to support cell growth are largely unknown. c-Fos, a well known AP …

We have previously shown that c-Fos activates phospholipid synthesis through a
mechanism independent of its genomic AP-1 activity. Herein, using PC12 cells induced to …

Immediate early genes are a family of genes that share the characteristic of having their
expression rapidly and transiently induced upon stimulation of neuronal and non-neuronal …

Purpose The development of myopia is controlled by still largely unknown retinal signals.
The aim of this study was to investigate the changes in retinal mRNA expression after …

ABSTRACT c‐Fos, a transcription factor that constitutes DNA‐binding AP‐1 complexes,
regulates gene expression that promotes long‐lasting cellular changes. We show that, in …

A shared characteristic of tumor cells is their exacerbated growth. Consequently, tumor cells
demand high rates of phospholipid synthesis required for membrane biogenesis to support …