Knowledge from London and Berlin: finding threads to a functional HIV cure

J Ding, Y Liu, Y Lai - Frontiers in Immunology, 2021 - frontiersin.org
Despite the ability of combination antiretroviral therapy (cART) to increase the life
expectancy of patients infected with human immunodeficiency virus (HIV), viral reservoirs …

[HTML][HTML] Secure transplantation by tissue purging using photodynamic therapy to eradicate malignant cells

S Moghassemi, A Dadashzadeh… - … of Photochemistry and …, 2022 - Elsevier
The field of photodynamic therapy (PDT) for treating various malignant neoplasms has been
given researchers' attention due to its ability to be a selective and minimally invasive cancer …

Glycolysis downregulation is a hallmark of HIV‐1 latency and sensitizes infected cells to oxidative stress

IL Shytaj, FA Procopio, M Tarek… - EMBO molecular …, 2021 - embopress.org
HIV‐1 infects lymphoid and myeloid cells, which can harbor a latent proviral reservoir
responsible for maintaining lifelong infection. Glycolytic metabolism has been identified as a …

Non-invasive plasma glycomic and metabolic biomarkers of post-treatment control of HIV

LB Giron, CS Palmer, Q Liu, X Yin… - Nature …, 2021 - nature.com
Non-invasive biomarkers that predict HIV remission after antiretroviral therapy (ART)
interruption are urgently needed. Such biomarkers can improve the safety of analytic …

Sirtuins as interesting players in the course of HIV infection and comorbidities

K Jurkowska, B Szymańska, B Knysz, A Kuźniarski… - Cells, 2021 - mdpi.com
The sirtuins (SIRTs) are a family of enzymes from the group of NAD+-dependent
deacetylases. Through the reaction of splitting the acetyl group of various transcription …

NAD deficiency contributes to progressive kidney disease in HIV-nephropathy mice

T Yoshida, K Myakala, BA Jones… - American Journal …, 2024 - journals.physiology.org
HIV disease remains prevalent in the United States and is particularly prevalent in sub-
Saharan Africa. Recent investigations revealed that mitochondrial dysfunction in kidney …

Photoinduced photosensitizer–antibody conjugates kill HIV env-expressing cells, also inactivating HIV

M Sadraeian, EF da Cruz, RW Boyle, C Bahou… - ACS …, 2021 - ACS Publications
HIV-infected cells persist for decades in patients administered with antiretroviral therapy
(ART). Meanwhile, an alarming surge in drug-resistant HIV viruses has been occurring …

CRISPR/CAS as a Powerful Tool for Human Immunodeficiency Virus Cure: A Review

S Vasconcelos Komninakis, W Domingues… - AIDS Research and …, 2024 - liebertpub.com
Despite care and the availability of effective antiretroviral treatment, some human
immunodeficiency virus (HIV)-infected individuals suffer from neurocognitive disorders …

Circulating immune and plasma biomarkers of time to HIV rebound in HIV controllers treated with vesatolimod

M Abdel-Mohsen, S Deeks, L Giron, KY Hong… - Frontiers in …, 2024 - frontiersin.org
Background Antiretroviral therapy (ART) for HIV-1 treatment has improved lifespan but
requires lifelong adherence for people living with HIV (PLWH), highlighting the need for a …

Immunogenicity of personalized dendritic-cell therapy in HIV-1 infected individuals under suppressive antiretroviral treatment: interim analysis from a phase II clinical …

MV de Almeida Baptista, LT da Silva, S Samer… - AIDS research and …, 2022 - Springer
Background We developed a personalized Monocyte-Derived Dendritic-cell Therapy
(MDDCT) for HIV-infected individuals on suppressive antiretroviral treatment and evaluated …