Purpose Intracytoplasmic sperm injection (ICSI) is the most widely utilized assisted
reproductive technique (ART) worldwide. In this feature, we review the early assisted …

Intracytoplasmic sperm injection (ICSI) has become the method of choice to overcome male
infertility when all other forms of assisted fertilization have failed. Animals in which ICSI has …

The objective of this study was to determine the incidence of DNA fragmentation in human
sperm, and to correlate any detected DNA damage with semen analysis parameters and …

Objective: To determine the incidence of DNA fragmentation in human sperm used for
intracytoplasmic sperm injection (ICSI) and to correlate any detected DNA damage with …

Egg activation, which is the first step in the initiation of embryo development, involves both
completion of meiosis and progression into mitotic cycles. In mammals, the fertilizing sperm …

In this study we investigated whether morphology and chromatin anomalies in human
spermatozoa can influence fertilization after intracytoplasmic sperm injection (ICSI). We …

Extensive chromatin reprogramming occurs at fertilization and is thought to be under the
control of maternal factors, but the underlying mechanisms remain poorly understood. We …

This study addresses the incidence of failed (0%) and suboptimal (< 50%) fertilization after
intracytoplasmic sperm injection (ICSI), variation in the ICSI fertilization rate for specific …

This study assessed pronuclear formation, the chromosomal constitution, and the
developmental capacity of bovine zygotes formed by intracytoplasmic injection of oocytes …

The aim of this study was to determine why oocytes remain unfertilized or develop three
pronuclei after intracytoplasmic sperm injection (ICSI). Unfertilized and abnormally fertilized …