Opening doors with ultrasound and microbubbles: Beating biological barriers to promote drug delivery

J Deprez, G Lajoinie, Y Engelen, SC De Smedt… - Advanced drug delivery …, 2021 - Elsevier
Apart from its clinical use in imaging, ultrasound has been thoroughly investigated as a tool
to enhance drug delivery in a wide variety of applications. Therapeutic ultrasound, as such …

[HTML][HTML] For whom the bubble grows: physical principles of bubble nucleation and dynamics in histotripsy ultrasound therapy

KB Bader, E Vlaisavljevich, AD Maxwell - Ultrasound in medicine & biology, 2019 - Elsevier
Histotripsy is a focused ultrasound therapy for non-invasive tissue ablation. Unlike thermally
ablative forms of therapeutic ultrasound, histotripsy relies on the mechanical action of …

Ultrasound‐propelled nanocups for drug delivery

JJ Kwan, R Myers, CM Coviello, SM Graham, AR Shah… - small, 2015 - Wiley Online Library
Ultrasound‐induced bubble activity (cavitation) has been recently shown to actively
transport and improve the distribution of therapeutic agents in tumors. However, existing …

Theranostic strategy of focused ultrasound induced blood-brain barrier opening for CNS disease treatment

KT Chen, KC Wei, HL Liu - Frontiers in pharmacology, 2019 - frontiersin.org
Focused Ultrasound (FUS) in combination with gaseous microbubbles has emerged as a
potential new means of effective drug delivery to the brain. Recent research has shown that …

A super‐resolution ultrasound method for brain vascular mapping

MA OˈReilly, K Hynynen - Medical physics, 2013 - Wiley Online Library
Purpose: High‐resolution vascular imaging has not been achieved in the brain due to
limitations of current clinical imaging modalities. The authors present a method for …

Thermometry and ablation monitoring with ultrasound

MA Lewis, RM Staruch, R Chopra - International Journal of …, 2015 - Taylor & Francis
In this review we present the current status of ultrasound thermometry and ablation
monitoring, with emphasis on the diverse approaches published in the literature and with an …

Nucleation, mapping and control of cavitation for drug delivery

E Stride, C Coussios - Nature Reviews Physics, 2019 - nature.com
Acoustically driven bubbles produce a range of mechanical, thermal and chemical effects
that can be exploited in drug delivery applications. Significant improvements in the targeting …

Quantitative frequency-domain passive cavitation imaging

KJ Haworth, KB Bader, KT Rich… - IEEE transactions on …, 2016 - ieeexplore.ieee.org
Passive cavitation detection has been an instrumental technique for measuring cavitation
dynamics, elucidating concomitant bioeffects, and guiding ultrasound therapies. Recently …

[图书][B] Therapeutic ultrasound

JM Escoffre, A Bouakaz - 2015 - Springer
Besides the well-known and wide use of ultrasound in diagnostics, the therapeutic use of
ultrasound has recently emerged. The understanding of the action of ultrasound waves at …

Passive acoustic mapping utilizing optimal beamforming in ultrasound therapy monitoring

C Coviello, R Kozick, J Choi, M Gyöngy… - The Journal of the …, 2015 - pubs.aip.org
Passive acoustic mapping (PAM) is a promising imaging method that enables real-time
three-dimensional monitoring of ultrasound therapy through the reconstruction of acoustic …