Depression is common, costly, debilitating, and associated with increased risk of suicide. It is
one of the leading global public health problems. Although existing available …

Depression is one of the most common comorbidities of many chronic medical diseases
including cancer and cardiovascular, metabolic, inflammatory and neurological disorders …

Objectives: To provide advice and guidance regarding the management of mood disorders,
derived from scientific evidence and supplemented by expert clinical consensus to formulate …

Update on Electroconvulsive Therapy ECT is effective for several disorders, particularly
severe or treatment-resistant depression, with a rapid response, but stigma has impeded its …

Background Transcranial direct current stimulation has shown promising clinical results,
leading to increased demand for an evidence-based review on its clinical effects. Objective …

Non-invasive brain stimulation (NIBS), including transcranial magnetic stimulation (TMS),
and transcranial direct current stimulation (tDCS), is a potentially effective treatment strategy …

Abstract Treatment-resistant depression (TRD) is a subset of Major Depressive Disorder
which does not respond to traditional and first-line therapeutic options. There are several …

Importance Treatment-resistant depression (TRD) is common in older adults. Bilateral
repetitive transcranial magnetic stimulation (rTMS) of the dorsolateral prefrontal cortex for 48 …

Background The degree of efficacy, safety, quality, and certainty of meta-analytic evidence of
biological non-pharmacological treatments in mental disorders is unclear. Methods We …

Bipolar disorders (BDs) are recurrent and sometimes chronic disorders of mood that affect
around 2% of the world's population and encompass a spectrum between severe elevated …