Apical-basal polarization in renal epithelial cells is crucial to renal function and an important
trigger for tubule formation in kidney development. Loss of polarity can induce epithelial-to …

The demand for transportation, driven by an increasing global population, is continuously
rising. This has led to a higher number of vehicles on the road and an increased reliance on …

The generation of plausible virtual patients (VPs) is an important step in most quantitative
systems pharmacology (QSP) workflows, which requires time-intensive solving of ordinary …

In this study, we present the application of fractional calculus (FC) in biomedicine. We
present three different integer order pharmacokinetic models which are widely used in …

The intention of this paper is to evaluate the influences of model parameters on the penicillin
fermentation process model. The existing sampling-based global sensitivity analysis (GSA) …

Cancer, a complex disease characterized by uncontrolled cell growth and metastasis,
remains a formidable challenge to global health. Mathematical modeling has emerged as a …

The construction of a mathematical model of a complicated system is often associated with
the evaluation of inputs'(arguments, factors) influence on the output (response), the …

In this study, we present the application of fractional calculus (FC) in biomedicine. We
present three different integer order pharmacokinetic models which are widely used in …

The demand for transportation, driven by an increasing global population, is continuously
rising. This has led to a higher number of vehicles on the road and an increased reliance on …

In the current work, we study two infectious disease models and we use nonlinear
optimization and optimal control theory which helps to find strategies towards transmission …