Exposure to early life stress (ELS) may lead to long-lasting neurobiological and behavioral
impairments. Alterations in the immune system and neuroinflammatory state induced by ELS …

Alzheimer's disease is a complex neurodegenerative disorder leading to a decline in
cognitive function and mental health. Recent research has positioned the gut microbiota as …

Understanding the interrelationship between the gut microbiota and host physiology,
although still in its relative infancy, has taken important steps forward over the past decade …

Background Mental disorders may be involved in neuroinflammatory processes that are
triggered by gut microbiota. How gut microbiota influence microglia-mediated sensitivity to …

Early-life stress (ELS) may affect brain maturation and neuroimmune interactions and,
consequently, the inflammatory response to subsequent environmental factors later in life …

Introduction The microbiota plays a critical role in modulating various aspects of host
physiology, particularly through the microbiota-gut-brain (MGB) axis. However, the …

Brain lipid dysregulation is a hallmark of depression and Alzheimer's disease, also marked
by chronic inflammation. Early-life stress (ELS) and dietary intake of polyunsaturated fatty …

To investigate the effects of one-week maternal separation (MS) on anxiety-and depression-
like behaviors in adolescent and adulthood as well as adult hippocampal metabolomics …

Stress, particularly during childhood, is a major risk factor for the development of depression.
Depression is twice as prevalent in women compared to men, which suggests that biological …

Traditional antibacterial hydrogels have a broad-spectrum bactericidal effect and are widely
used as wound dressings. However, the biological toxicity and drug resistance of these …