CD8 T-cell subsets: heterogeneity, functions, and therapeutic potential

CH Koh, S Lee, M Kwak, BS Kim… - Experimental & Molecular …, 2023 - nature.com
CD8 T cells play crucial roles in immune surveillance and defense against infections and
cancer. After encountering antigenic stimulation, naïve CD8 T cells differentiate and acquire …

The role of interleukin-22 in lung health and its therapeutic potential for COVID-19

S Fang, D Ju, Y Lin, W Chen - Frontiers in immunology, 2022 - frontiersin.org
Although numerous clinical trials have been implemented, an absolutely effective treatment
against coronavirus disease 2019 (COVID-19) is still elusive. Interleukin-22 (IL-22) has …

Dynamics of inflammatory responses after SARS-CoV-2 infection by vaccination status in the USA: a prospective cohort study

X Zhu, KA Gebo, AG Abraham, F Habtehyimer… - The Lancet …, 2023 - thelancet.com
Background Cytokines and chemokines play a critical role in the response to infection and
vaccination. We aimed to assess the longitudinal association of COVID-19 vaccination with …

Effect of antiviral and immunomodulatory treatment on a cytokine profile in patients with COVID-19

D Martonik, A Parfieniuk-Kowerda, A Starosz… - Frontiers in …, 2023 - frontiersin.org
Background The severity of COVID-19 is associated with an elevated level of a variety of
inflammatory mediators. Increasing evidence suggests that the Th17 response contributes to …

Characterization of IL-10 Family of Cytokines in Acute and Convalescent COVID-19 Individuals

A Rajamanickam, PK Nathella, N Selvaraj… - Journal of Interferon & …, 2023 - liebertpub.com
Cytokines are major players in orchestrating inflammation, disease pathogenesis, and
severity during COVID-19. Members of the interleukin (IL)-10 family of cytokines play …

Unraveling the dynamic mechanisms of natural killer cells in viral infections: insights and implications

A Letafati, OS Ardekani, M Naderisemiromi, M Norouzi… - Virology Journal, 2024 - Springer
Viruses pose a constant threat to human well-being, necessitating the immune system to
develop robust defenses. Natural killer (NK) cells, which play a crucial role in the immune …

Comprehensive analyses of immune activity in COVID-19-vaccinated idiopathic pulmonary fibrosis patients

A Maciejewska, P Czernia… - Frontiers in …, 2025 - frontiersin.org
Idiopathic pulmonary fibrosis (IPF) is a progressive and fatal disease, characterized by
impaired wound repair, tissue remodeling and fibrosis. Immune system may participate in …

Impact of Prior COVID-19 Immunization and/or Prior Infection on Immune Responses and Clinical Outcomes

A Livieratos, C Gogos, K Akinosoglou - Viruses, 2024 - mdpi.com
Cellular and humoral immunity exhibit dynamic adaptation to the mutating SARS-CoV-2
virus. It is noteworthy that immune responses differ significantly, influenced by whether a …

Assessment of immune responses to a Comirnaty® booster following CoronaVac® vaccination in healthcare workers

L Bochnia-Bueno, GM Coelho… - Memórias do Instituto …, 2024 - SciELO Brasil
BACKGROUND The immunological response to severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) infection and immunisation is variable. OBJECTIVES To …

Crossroads between Autoimmunity and COVID-19 in Lung Transplant Recipients

M Narasimhan, A Muthukumar, K Sataranatarajan… - Viruses, 2023 - mdpi.com
The presence of a certain group of auto-antibodies (AAbs) is known to correlate with the
severity of COVID-19. It is, however, unknown if such AAbs are prevalent and impact COVID …