The effects of polyphenols and other bioactives on human health

CG Fraga, KD Croft, DO Kennedy… - Food & function, 2019 - pubs.rsc.org
Although deficiencies in polyphenol intake do not result in specific deficiency diseases,
adequate intake of polyphenols could confer health benefits, especially with regard to …

Sources of vascular nitric oxide and reactive oxygen species and their regulation

J Tejero, S Shiva, MT Gladwin - Physiological reviews, 2019 - journals.physiology.org
Nitric oxide (NO) is a small free radical with critical signaling roles in physiology and
pathophysiology. The generation of sufficient NO levels to regulate the resistance of the …

The bioavailability, transport, and bioactivity of dietary flavonoids: A review from a historical perspective

G Williamson, CD Kay, A Crozier - Comprehensive Reviews in …, 2018 - Wiley Online Library
Flavonoids are plant‐derived dietary components with a substantial impact on human
health. Research has expanded massively since it began in the 1930s, and the complex …

Polyphenols and neuroprotection: Therapeutic implications for cognitive decline

G Caruso, SA Torrisi, MP Mogavero, W Currenti… - Pharmacology & …, 2022 - Elsevier
Dietary polyphenols have been the focus of major interest for their potential benefits on
human health. Several preclinical studies have been conducted to provide a rationale for …

Strategies to increase nitric oxide signalling in cardiovascular disease

JO Lundberg, MT Gladwin, E Weitzberg - Nature reviews Drug …, 2015 - nature.com
Nitric oxide (NO) is a key signalling molecule in the cardiovascular, immune and central
nervous systems, and crucial steps in the regulation of NO bioavailability in health and …

Flavor chemistry of cocoa and cocoa products—an overview

AC Aprotosoaie, SV Luca… - Comprehensive reviews in …, 2016 - Wiley Online Library
Cocoa originates from beans of the cocoa tree (Theobroma cacao L.) and it is an important
commodity in the world and the main ingredient in chocolate manufacture. Its value and …

Bioavailability, bioactivity and impact on health of dietary flavonoids and related compounds: an update

A Rodriguez-Mateos, D Vauzour, CG Krueger… - Archives of …, 2014 - Springer
There is substantial interest in the role of plant secondary metabolites as protective dietary
agents. In particular, the involvement of flavonoids and related compounds has become a …

Therapies for prevention and treatment of Alzheimer's disease

J Mendiola-Precoma, LC Berumen… - BioMed research …, 2016 - Wiley Online Library
Alzheimer's disease (AD) is the most common cause of dementia associated with a
progressive neurodegenerative disorder, with a prevalence of 44 million people throughout …

[HTML][HTML] Cocoa flavanol consumption improves cognitive function, blood pressure control, and metabolic profile in elderly subjects: the Cocoa, Cognition, and Aging …

D Mastroiacovo, C Kwik-Uribe, D Grassi… - The American journal of …, 2015 - Elsevier
Background: Recent evidence has indicated that flavanol consumption may have many
health benefits in humans, including improved cognitive activities. Objective: The aim was to …

Rationale for a multi-factorial approach for the reversal of cognitive decline in Alzheimer's disease and MCI: a review

RV Rao, KG Subramaniam, J Gregory… - International Journal of …, 2023 - mdpi.com
Alzheimer's disease (AD) is a multifactorial, progressive, neurodegenerative disease
typically characterized by memory loss, personality changes, and a decline in overall …