The mechanism of genome replication and transcription in bunyaviruses

H Malet, HM Williams, S Cusack, M Rosenthal - PLoS pathogens, 2023 - journals.plos.org
Bunyaviruses are negative sense, single-strand RNA viruses that infect a wide range of
vertebrate, invertebrate and plant hosts. WHO lists three bunyavirus diseases as priority …

IFITMs restrict the replication of multiple pathogenic viruses

JM Perreira, CR Chin, EM Feeley, AL Brass - Journal of molecular biology, 2013 - Elsevier
The interferon-inducible transmembrane protein (IFITM) family inhibits a growing number of
pathogenic viruses, among them influenza A virus, dengue virus, hepatitis C virus, and …

Transcription and replication mechanisms of Bunyaviridae and Arenaviridae L proteins

F Ferron, F Weber, JC de la Torre, J Reguera - Virus research, 2017 - Elsevier
Bunyaviridae and Arenaviridae virus families include an important number of highly
pathogenic viruses for humans. They are enveloped viruses with negative stranded RNA …

Fat, fight, and beyond: The multiple roles of lipid droplets in infections and inflammation

FS Pereira-Dutra, L Teixeira… - Journal of leukocyte …, 2019 - academic.oup.com
Increased accumulation of cytoplasmic lipid droplets (LDs) in host nonadipose cells is
commonly observed in response to numerous infectious diseases, including bacterial …

The virus–host interplay in Junín mammarenavirus infection

GL Gallo, N López, ME Loureiro - Viruses, 2022 - mdpi.com
Junín virus (JUNV) belongs to the Arenaviridae family and is the causative agent of
Argentine hemorrhagic fever (AHF), a severe human disease endemic to agricultural areas …

Lassa virus, but not highly pathogenic New World arenaviruses, restricts immunostimulatory double-stranded RNA accumulation during infection

EJ Mateer, J Maruyama, GE Card, S Paessler… - Journal of …, 2020 - Am Soc Microbiol
The arenaviruses Lassa virus (LASV), Junín virus (JUNV), and Machupo virus (MACV) can
cause severe and fatal diseases in humans. Although these pathogens are closely related …

Segmented negative strand RNA virus nucleoprotein structure

J Reguera, S Cusack, D Kolakofsky - Current opinion in virology, 2014 - Elsevier
Highlights•In monomeric nucleoproteins not bound to RNA, the positive charged RNA
binding groove is filled intra-molecularly.•NP oligomerisation occurs when intra-molecular …

Structural insight into nucleoprotein conformation change chaperoned by VP35 peptide in Marburg virus

B Liu, S Dong, G Li, W Wang, X Liu, Y Wang… - Journal of …, 2017 - Am Soc Microbiol
Marburg virus (MARV) encodes a nucleoprotein (NP) to encapsidate its genome by
oligomerization and form a ribonucleoprotein complex (RNP). According to previous …

Visualization of double-stranded RNA colocalizing with pattern recognition receptors in arenavirus infected cells

EJ Mateer, S Paessler, C Huang - Frontiers in cellular and infection …, 2018 - frontiersin.org
An important step in the initiation of the innate immune response to virus infection is the
recognition of non-self, viral RNA, including double-stranded RNA (dsRNA), by cytoplasmic …

Brothers in Arms: Structure, Assembly and Function of Arenaviridae Nucleoprotein

N Papageorgiou, M Spiliopoulou, THV Nguyen… - Viruses, 2020 - mdpi.com
Arenaviridae is a family of viruses harbouring important emerging pathogens belonging to
the Bunyavirales order. Like in other segmented negative strand RNA viruses, the …