Archived patient-derived tissue specimens play a central role in understanding disease and
developing therapies. To address specificity and sensitivity shortcomings of existing single …

Circulating tumor cells (CTCs) in peripheral blood have been recognized as a general
biomarker for diagnosing cancer and providing guidance for personalized treatments. Yet …

New tools that facilitate the study of cell-to-cell variability could help uncover novel cellular
regulation mechanisms. We present an integrated microfluidic platform to analyze a large …

Here, we report a new method for multicomponent protein patterning in a microchannel and
also a technique for improving immunoaffinity-based circulating tumor cell (CTC) capture by …

Cancer cell detection with high capture efficiency is important for its extensive clinical
applications. Herringbone structures in microfluidic devices have been widely adopted to …

With the use of cell replacement therapies as a realistic prospect for conditions such as
Parkinson's and Huntington's diseases, the logistics of the delivery of cell suspensions to …

It is desired to understand the effect of alginic acid sodium salt from brown algae (alginate)
as a viscosity modifier on the behavior of blood in vitro using a micro-particle image …

Cell permeability controls the transportation of extracellular materials through cell
membranes, which plays a critical role in drug and gene delivery. This work reports an …

Isolation of cells from blood is critical for vast biomedical applications. The focus of this
dissertation is on the isolation of circulating tumor cells (CTCs) from patient blood, which …

Rapid and accurate detection, quantification and analysis of rare cells in biological samples
is of critical importance for a variety of clinical applications. These cells, which can be …